Articles


2022


81. Bhosale, V. A.; Císařová, I.; Kamlar, M.; Veselý, J. "Catalytic asymmetric addition to cyclic N-acyl-iminium: access to sulfone-bearing contiguous quaternary stereocenters" Chem. Commun., 2022, 58, 9942–9945.

https://doi.org/10.1039/D2CC02667H

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Available positions in our research group:

We are looking to recruit motivated and committed scientists. If you are interested in working in our group please contact us directly. 

PhD positions: 

PhD positions are available in our group each year, usually starting in September. If you are interested in a PhD in our group then please do not hesitate to contact us.

MSc and Bc positions: 

Contact

Address

Department of Organic Chemistry

Faculty of Science, Charles University in Prague

Hlavova 8

128 43 Prague 2

Czech Republic

Phone: +420 221 951 305

e-mail: jan.vesely@natur.cuni.cz

Research

Enantioselective Catalysis - New Reaction Methods - Synthesis of Biologically Active Compounds

Research program of our laboratory aims to identifiy a novel reactivity using oranocatalytic approach towards enantiomerically pure compounds from simple and readily available starting materials.

The main objective is focused on the development of new stereocontrolled synthetic methodologies using diffenrent activation modes in organocatalysis to prepare highly functionalized organic molecules with a special emphasis on the synthesis of spirocyclic molecules bearing heterocyclic moiety.

The main feature in the field of organocatalysis remains in covalent aminocatalysis, H-bonding catalysis and Brønsted acid catalysis.

We are also interested in combining organocatalytic approach in activation of molecules with metal catalysis which might lead to the discovery of reactions that are not accessible with either type of catalyst alone.

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