Enantioselective Catalysis - New Reaction Methods - Synthesis of Biologically Active Compounds

Research program of our laboratory aims to identifiy a novel reactivity using oranocatalytic approach towards enantiomerically pure compounds from simple and readily available starting materials.

The main objective is focused on the development of new stereocontrolled synthetic methodologies using diffenrent activation modes in organocatalysis to prepare highly functionalized organic molecules with a special emphasis on the synthesis of spirocyclic molecules bearing heterocyclic moiety.

The main feature in the field of organocatalysis remains in covalent aminocatalysis, H-bonding catalysis and Brønsted acid catalysis.

We are also interested in combining organocatalytic approach in activation of molecules with metal catalysis which might lead to the discovery of reactions that are not accessible with either type of catalyst alone.


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