Publications

Balintová, J.; Plucnara, M.; Vidláková, P.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M. Benzofurazane as a New Redox Label for Electrochemical Detection of DNA: Towards Multipotential Redox Coding of DNA Bases. Chemistry - A European Journal 2013, 19 (38), 12720-12731 DOI: 10.1002/chem.201301868.

Dadová, J.; Vrábel, M.; Adámik, M.; Brázdová, M.; Pohl, R.; Fojta, M.; Hocek, M. Azidopropylvinylsulfonamide as a New Bifunctional Click Reagent for Bioorthogonal Conjugations: Application for DNA-Protein Cross-Linking. Chemistry - A European Journal 2015, 21 (45), 16091-16102 DOI: 10.1002/chem.201502209.

Balintová, J.; Špaček, J.; Pohl, R.; Brázdová, M.; Havran, L.; Fojta, M.; Hocek, M. Azidophenyl as a click-transformable redox label of DNA suitable for electrochemical detection of DNA–protein interactions. Chem. Sci. 2015, 6 (1), 575-587 DOI: 10.1039/C4SC01906G.

Bricout, H.; Caronia, E.; Galia, A.; Tichá, I. Chena; Jindřich, J.; Léger, B.; Menuel, S.; Monflier, É.; Noël, S.; Ponchel, A.; et al. Asymmetric hydrogenation of ethyl pyruvate over aqueous dispersed Pt nanoparticles stabilized by a cinchonidine-functionalized β-cyclodextrin. Catalysis Communications 2021, 150 (February), nestránkováno.

Číhalová, S.; Dziedzic, P.; Córdova, A.; Vesely, J. Asymmetric Aza-Morita-Baylis-Hillman-Type Reactions: The Highly Enantioselective Reaction between Unmodified α,β- Unsaturated Aldehydes and N-Acylimines by Organo-co-catalysis. Advanced Synthesis & Catalysis 2011, 353 (7), 1096-1108 DOI: 10.1002/adsc.201000951.

Kamlar, M.; Císařová, I.; Hybelbauerová, S.; Vesely, J. Asymmetric Allylic Amination of Morita-Baylis-Hillman Carbonates with Silylated tert-Butylhydroxycarbamate Derivatives. European Journal of Organic Chemistry 2017, No. 14, 1926-1930 DOI: 10.1002/ejoc.201700222.

Dadová, J.; Vidláková, P.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M. Aqueous Heck Cross-Coupling Preparation of Acrylate-Modified Nucleotides and Nucleoside Triphosphates for Polymerase Synthesis of Acrylate-Labeled DNA. The Journal of Organic Chemistry 2013, 78 (19), 9627-9637 DOI: 10.1021/jo4011574.

Bednářová, E.; Kotora, M.; Malatinec, Š. Applications of Bolm's Ligand in Enantioselective Synthesis. Molecules 2020, 25 (4), nestránkováno DOI: 10.3390/molecules25050958.

Bouřa, E.; Čížek, K.; Eyer, L.; Hocek, M.; Hodek, J.; Konkoľová, E.; Kozák, J.; Milisavljević, N.; Nencka, R.; Pohl, R.; et al. Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses. ACS Infectious Diseases 2021, 7 (2), 471-478.

Císařová, I.; Holovko-Kamoshenkova, O. M.; Hrdina, R.; Koucký, F.; Machalický, O. Annulated carbamates are precursors for the ring contraction of the adamantane framework. RSC Advances [online] 2022, 12 (48), 31056-31060.

Roeser, J.; Prill, D.; Bojdys, M. J.; Fayon, P.; Trewin, A.; Fitch, A. N.; Schmidt, M. U.; Thomas, A. Anionic silicate organic frameworks constructed from hexacoordinate silicon centres. Nature Chemistry 2017, 9 (10), 977-982 DOI: 10.1038/NCHEM.2771.

Šnajdr, I.; Janoušek, Z.; Takagaki, M.; Císařová, I.; Hosmane, N. S.; Kotora, M. Alpha (α-) and beta (β-carboranyl-C-deoxyribosides: Syntheses, structures and biological evaluation. European Journal of Medicinal Chemistry 2014, 83, 389-397 DOI: 10.1016/j.ejmech.2014.06.005.

Kamlar, M.; Císařová, I.; Veselý, J. Alkynylation of heterocyclic compounds using hypervalent iodine reagent. Org. Biomol. Chem. 2015, 13 (10), 2884-2889 DOI: 10.1039/C4OB02625J.

Slavíčková, M.; Pohl, R.; Hocek, M. Additions of Thiols to 7-Vinyl-7-deazaadenine Nucleosides and Nucleotides. Synthesis of Hydrophobic Derivatives of 2′-Deoxyadenosine, dATP and DNA. The Journal of Organic Chemistry 2016, 81 (22), 11115-11125 DOI: 10.1021/acs.joc.6b02098.

Holy, A.; Dvorakova, H.; Jindrich, J.; Masojidkova, M.; Budesinsky, M.; Balzarini, J.; Andrei, G.; DeClercq, E. Acyclic Nucleotide Analogs Derived from 8-Azapurines:  Synthesis and Antiviral Activity. Journal of Medicinal Chemistry 1996, 39 (20), 4073-4088 DOI: 10.1021/jm960314q.

Břehová, P.; Česnek, M.; Dračínský, M.; Chaloupecká, E.; Janeba, Z.; Mertlíková-Kaiserová, H.; Skácel, J.; Soto-Velasquez, M. P.; Tloušťová, E.; Watts, V. J. Acyclic nucleoside phosphonates with 2-aminothiazole base as inhibitors of bacterial and mammalian adenylate cyclases. European Journal of Medicinal Chemistry 2021, 222 (October 15 2021), nestránkováno.

Fadeev, A.; Makarov, A. S.; Uchuskin, M. G. Acid-Catalyzed Cascade Reaction of 2-Alkylfurans with α,β-Unsaturated Ketones: A Shortcut to 2,3,5-Trisubstituted Furans. Journal of Organic Chemistry 2021, 86 (23), 17362-17370.

Císařová, I.; Formánek, B.; Tauchman, J.; Vesely, J. Access to Spirocyclic Benzothiophenones with Multiple Stereocenters via an Organocatalytic Cascade Reaction. Journal of Organic Chemistry 2020, 85 (13), 8510-8521 DOI: 10.1021/acs.joc.0c00882.

Balzarini, J.; Holy, A.; Jindrich, J. J.; Dvorakova, H.; Hao, Z.; Snoeck, R.; Herdewijn, P.; Johns, D. G.; De Clercq, E. 9-[(2RS)-3-Fluoro-2-phosphonylmethoxypropyl] derivatives of Purines - A Class of Highly Selective Antiretroviral Agents Invitro and Invivo. Proceedings of the National Aacademy of Sciences of the United States of America 1991, 88 (11), 4961-4965.

Kielkowski, P.; Fanfrlík, J.; Hocek, M. 7-Aryl-7-deazaadenine 2′-Deoxyribonucleoside Triphosphates (dNTPs): Better Substrates for DNA Polymerases than dATP in Competitive Incorporations. Angewandte Chemie International Edition 2014, 53 (29), 7552-7555 DOI: 10.1002/anie.201404742.

Perlikova, P.; Rylova, G.; Naus, P.; Elbert, T.; Tloustova, E.; Bourderioux, A.; Slavetinska, L. P.; Motyka, K.; Dolezal, D.; Znojek, P.; et al. 7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action. Molecular Cancer Therapeutics 2016, 15 (5), 922-937 DOI: 10.1158/1535-7163.MCT-14-0933.

Bosáková, A.; Perlíková, P.; Tichý, M.; Pohl, R.; Hocek, M. 6-Aryl-4-amino-pyrimido[4,5-b]indole 2′-deoxyribonucleoside triphosphates (benzo-fused 7-deaza-dATP analogues): Synthesis, fluorescent properties, enzymatic incorporation into DNA and DNA-protein binding study. Bioorganic & Medicinal Chemistry 2016, 24 (19), 4528-4535 DOI: 10.1016/j.bmc.2016.07.054.

Perlíková, P.; Konečný, P.; Nauš, P.; Snášel, J.; Votruba, I.; Džubák, P.; Pichová, I.; Hajdúch, M.; Hocek, M. 6-Alkyl-, 6-aryl- or 6-hetaryl-7-deazapurine ribonucleosides as inhibitors of human or MTB adenosine kinase and potential antimycobacterial agents. MedChemComm 2013, 4 (11), 1497 DOI: 10.1039/c3md00232b.

Cahová, H.; Panattoni, A.; Kielkowski, P.; Fanfrlík, J.; Hocek, M. 5-Substituted Pyrimidine and 7-Substituted 7-Deazapurine dNTPs as Substrates for DNA Polymerases in Competitive Primer Extension in the Presence of Natural dNTPs. ACS Chemical Biology 2016, 11 (11), 3165-3171 DOI: 10.1021/acschembio.6b00714.

Janoušková, M.; Vaníková, Z.; Nici, F.; Boháčová, S.; Vitovska, D.; Šanderová, H.; Hocek, M.; Krásný, L. 5-(Hydroxymethyl) uracil and -cytosine as potential epigenetic marks enhancing or inhibiting transcription with bacterial RNA polymerase. Chemical Communications 2017, 53 (99), 13253-13255 DOI: 10.1039/c7cc08053k.