Publications

A. Downey, M.; Richter, C.; Pohl, R.; Mahrwald, R.; Hocek, M. Direct One-Pot Synthesis of Nucleosides from Unprotected or 5-O-Monoprotected D-Ribose. Organic Letters 2015, 17 (18), 4604-4607 DOI: 10.1021/acs.orglett.5b02332.

Kaiser, R. P.; Ulc, J.; Císařová, I.; Necas, D. Direct regioselective C-H borylation of [5]helicene. Rsc Advances 2018, 8 (1), 580-583 DOI: 10.1039/c7ra13021j.

Machara, A.; D. Cox, P.; Hudlicky, T. Direct Synthesis of Naltrexone by Palladium-Catalyzed N -Demethylation/Acylation of Oxymorphone: The Benefit of CH Activation and the Intramolecular Acyl Transfer from C-14 Hydroxy. Advanced Synthesis & Catalysis 2012, 354 (14-15), 2713-2718 DOI: 10.1002/adsc.201200677.

Machara, A.; Endoma-Arias, M. Ann A.; Císařová, I.; D. Cox, P.; Hudlicky, T. Direct Synthesis of Noroxymorph­one from Thebaine: Unusual Ce ^IV Oxidation of a Methoxydiene-Iron Complex to an Enone-γ-Nitrate. European Journal of Organic Chemistry 2016, 2016 (8), 1500-1503 DOI: 10.1002/ejoc.201600153.

Novotná, K.; Tenora, L.; Prchalová, E.; Paule, J.; Alt, J.; Veeravalli, V.; Lam, J.; Wu, Y.; Šnajdr, I.; Gori, S.; et al. Discovery of tert-Butyl Ester Based 6-Diazo-5-oxo-l-norleucine Prodrugs for Enhanced Metabolic Stability and Tumor Delivery. Journal of Medicinal Chemistry 2023, 66 (22), 15493-15510.

Kocek, H.; Chalupská, D.; Dejmek, M.; Dvořáková, A.; Zgarbová, M.; Šála, M.; Chalupský, K.; Krafčíková, P.; Otava, T.; Drexler, M.; et al. Discovery of highly potent SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5′-carboxamides. RSC Medicinal Chemistry 2024, nestránkováno.

Baszczyňski, O.; Dračínský, M.; Dvořáková, A.; Hodek, J.; Chalupský, K.; Janeba, Z.; Kalčic, F.; Kaiserová, H. Mertlíkov; Strmeň, T.; Šebestík, J.; et al. Discovery of Modified Amidate (ProTide) Prodrugs of Tenofovir with Enhanced Antiviral Properties. Journal of Medicinal Chemistry 2021, 64 (22), 16425-16449.

Dračínský, M.; Drastík, M.; Kašpar, M.; Klepetářová, B.; Kronenberger, T.; Kudová, E.; Mičuda, S.; Pávek, P.; Štefela, A. (E)-7-Ethylidene-lithocholic Acid (7-ELCA) Is a Potent Dual Farnesoid X Receptor (FXR) Antagonist and GPBAR1 Agonist Inhibiting FXR-Induced Gene Expression in Hepatocytes and Stimulating Glucagon-like Peptide-1 Secretion From Enteroendocrine Cells. Frontiers in Pharmacology 2021, 12 (August), nestránkováno.

Hrdina, R.; Kadlcikova, A.; Valterová, I.; Hodačová, J.; Kotora, M. An easy route to atropoisomeric bipyridine N,N′-dioxides and allylation of aldehydes. Tetrahedron: Asymmetry 2006, 17 (22), 3185-3191 DOI: 10.1016/j.tetasy.2006.11.025.

Kočková, O.; Kasal, P.; Zelený, J.; Walterova, Z.; Vlčková, V.; Jindřich, J. Effect of Counterions on the Soft Ionization Mass Spectra of Analytes with Multiple Permanent Charges. Analytical Chemistry 2024, 96 (18), 6940-6946.

Veselý, O.; Živný, M.; Nigríni, M.; Veselý, J.; Čejka, J. The effect of the active site and substrate structure in preparation of substituted tetrahydropyrans via intramolecular cyclization. Catalysis Today 2024, 429 (March).

Hartmann, K.; Kuffer, M.; Balzarini, J.; Naesens, L.; Goldberg, M.; Erfle, V.; Goebel, F. D.; De Clercq, E.; Jindrich, J.; Holy, A.; et al. Efficacy of the acyclic nucleoside phosphonates (S)-9-(3-fluoro-2-phosphonylmethoxypropyl)adenine (FPMPA) and 9-(2-phosphonylmethoxyethyl)adenine (PMEA) against feline immunodeficiency virus. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology 1998, 17 (2), 120-128.

Holovko-Kamoshenkova, O. M.; Slivka, M. V.; Hrdina, R.; Baumer, V. N.; Korol, N. I.; Sokolenko, L. V.; Lendel, V. G. An Efficient Catalyst-Free Direct Approach to 5-Polyfluoroalkyl-1,2,4-triazole-3-thiones. Synthesis 2023, 55 (08), 1221-1226.

Veith, G. M.; Baggetto, L.; Adamczyk, L. A.; Guo, B.; Brown, S. S.; Sun, X. - G.; Albert, A. A.; Humble, J. R.; Barnes, C. E.; Bojdys, M. J.; et al. Electrochemical and Solid-State Lithiation of Graphitic C ₃ N ₄. Chemistry of Materials 2013, 25 (3), 503-508 DOI: 10.1021/cm303870x.

Danhel, A.; Raindlová, V.; Havran, L.; Pivonkova, H.; Hocek, M.; Fojta, M. Electrochemical behaviour of 2,4-dinitrophenylhydrazi(o)ne as multi-redox centre DNA label at mercury meniscus modified silver solid amalgam electrode. Electrochimica Acta 2014, 126, 122-131 DOI: 10.1016/j.electacta.2013.09.147.

Spampinato, A.; Kužmová, E.; Pohl, R.; Sýkorová, V.; Vrábel, M.; Kraus, T.; Hocek, M. trans-Cyclooctene- and Bicyclononyne-Linked Nucleotides for Click Modification of DNA with Fluorogenic Tetrazines and Live Cell Metabolic Labeling and Imaging. Bioconjugate Chemistry 2023, 34 (4), 772-780.

Belhajová, M.; Vícha, A.; Burgert, L.; Brožková, I.; Michaličková, L.; Hrdina, R.; Moravec, T.; Netuka, D.; Musil, Z.; Hrdina, R. En route to local glioblastoma treatment with temozolomide doped hyaluronan fibres: formulation and in vitro cell studies. RSC Medicinal Chemistry 2023, 14 (9), 1662-1666.

Nigríni, M.; Bhosale, V. Anandrao; Císařová, I.; Veselý, J. Enantioenriched 1,4-Benzoxazepines via Chiral Brønsted Acid-Catalyzed Enantioselective Desymmetrization of 3-Substituted Oxetanes. Journal of Organic Chemistry 2023, 88 (24), 17024-17036.

Urban, M.; Franc, M.; Hofmanova, M.; Císařová, I.; Veselý, J. The enantioselective addition of 1-fluoro-1-nitro (phenylsulfonyl) methane to isatin-derived ketimines. Organic & Biomolecular Chemistry 2017, 15 (43), 9071-9076 DOI: 10.1039/c7ob02408h.

Koukal, P.; Kotora, M. Enantioselective Allylation of (2E,4E)-2,4-Dimethylhexadienal: Synthesis of (5R,6S)-(+)-Pteroenone. Chemistry - A European Journal 2015, 21 (20), 7408-7412 DOI: 10.1002/chem.201500050.

Vlašaná, K.; Hrdina, R.; Valterová, I.; Kotora, M. Enantioselective Allylation of Aldehydes Catalyzed by Diastereoisomeric Bis(tetrahydroisoquinoline) N,N′-Dioxides. European Journal of Organic Chemistry 2010, 2010 (36), 7040-7044 DOI: 10.1002/ejoc.201001219.

Hessler, F.; Betík, R.; Kadlcikova, A.; Belle, R.; Kotora, M. Enantioselective Allylation of Selected ortho-Substituted Benzaldehydes: A Comparative Study. European Journal of Organic Chemistry 2014, 2014 (32), 7245-7252 DOI: 10.1002/ejoc.201403034.

Cadart, T.; Koukal, P.; Kotora, M. Enantioselective Allylation of tert-Butyldimethylsilyl-Protected Vanillin and Synthesis of a Lignan Derivative Isolated from Machilus wangchiana. European Journal of Organic Chemistry 2014, 2014 (34), 7556-7560 DOI: 10.1002/ejoc.201403094.

Motloch, P.; Valterová, I.; Kotora, M. Enantioselective Allylation of Thiophene-2-carbaldehyde: Formal Total Synthesis of Duloxetine. Advanced Synthesis & Catalysis 2014, 356 (1), 199-204 DOI: 10.1002/adsc.201300849.

Koukal, P.; Ulč, J.; Nečas, D.; Kotora, M. Enantioselective Allylation of β-Haloacrylaldehydes: Formal Total Syntheses of Pteroenone and Antillatoxin. European Journal of Organic Chemistry 2016, 2016 (12), 2110-2114 DOI: 10.1002/ejoc.201600286.