Publications

Machara, A.; Lux, V.; Kožíšek, M.; Šašková, K. Grantz; Štěpánek, O.; Kotora, M.; Parkan, K.; Pávová, M.; Glass, B.; Sehr, P.; et al. Specific Inhibitors of HIV Capsid Assembly Binding to the C-Terminal Domain of the Capsid Protein: Evaluation of 2-Arylquinazolines as Potential Antiviral Compounds. Journal of Medicinal Chemistry 2016, 59 (2), 545-558 DOI: 10.1021/acs.jmedchem.5b01089.

Mikušek, J.; Matouš, P.; Matoušová, E.; Janoušek, M.; Kuneš, J.; Pour, M. Substrate Control in the Gold(I)-Catalyzed Cyclization of β - Propargylamino Acrylic Esters and Further Transformations of the Resultant Dihydropyridines. Advanced Synthesis & Catalysis 2016, 358 (18), 2912-2922 DOI: 10.1002/adsc.201600412.

Mikušek, J.; Matouš, P.; Matoušová, E.; Janoušek, M.; Kuneš, J.; Pour, M. Substrate Control in the Gold(I)-Catalyzed Cyclization of β - Propargylamino Acrylic Esters and Further Transformations of the Resultant Dihydropyridines. Advanced Synthesis & Catalysis 2016, 358 (18), 2912-2922 DOI: 10.1002/adsc.201600412.

Mikušek, J.; Matouš, P.; Matoušová, E.; Janoušek, M.; Kuneš, J.; Pour, M. Substrate Control in the Gold(I)-Catalyzed Cyclization of β - Propargylamino Acrylic Esters and Further Transformations of the Resultant Dihydropyridines. Advanced Synthesis & Catalysis 2016, 358 (18), 2912-2922 DOI: 10.1002/adsc.201600412.

Benkovics, G.; Hodek, O.; Havlikova, M.; Bosakova, Z.; Coufal, P.; Malanga, M.; Fenyvesi, E.; Darcsi, A.; Beni, S.; Jindřich, J. Supramolecular structures based on regioisomers of cinnamyl-α-cyclodextrins – new media for capillary separation techniques. Beilstein Journal of Organic Chemistry 2016, 12, 97-109 DOI: 10.3762/bjoc.12.11.

Sabat, N.; Nauš, P.; Matyašovský, J.; Dziuba, D.; Slavětínská, L.; Hocek, M. Synthesis of Fluorescent 2-Substituted 6-(Het)aryl-7-deazapurine Bases {4-(Het)aryl-pyrrolo[2,3-d]pyrimidines} by Aqueous Suzuki–Miyaura Cross-Coupling Reactions. Synthesis 2016, 48 (07), 1029-1045 DOI: 10.1055/s-0035-1561287.

Machara, A.; Endoma-Arias, M.; Císařová, I.; Cox, D.; Hudlicky, T. Synthesis of Nororipavine and Noroxymorphone via N- and O-Demethylation of Iron Tricarbonyl Complex of Thebaine. Synthesis 2016, 48 (12), e1-e1 DOI: 10.1055/s-0035-1562345.

Kaiser, R. P.; Hessler, F.; Mosinger, J.; Císařová, I.; Kotora, M. A [2+2+2]-Cyclotrimerization Approach to Selectively Substituted Fluorenes and Fluorenols, and Their Conversion to 9,9′-Spirobifluorenes. Chemistry - A European Journal 2015, 21 (39), 13577-13582 DOI: 10.1002/chem.201502370.

Malnuit, V.; Slavětínská, L. Poštová; Nauš, P.; Džubák, P.; Hajdúch, M.; Stolaříková, J.; Snášel, J.; Pichová, I.; Hocek, M. 2-Substituted 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Inhibition of Adenosine Kinases, and Antimycobacterial Activity. ChemMedChem 2015, 10 (6), 1079-1093 DOI: 10.1002/cmdc.201500081.

Olszewska, A.; Dadová, J.; Mačková, M.; Hocek, M. Cleavage of DNA containing 5-fluorocytosine or 5-fluorouracil by type II restriction endonucleases. Bioorganic & Medicinal Chemistry 2015, 23 (21), 6885-6890 DOI: 10.1016/j.bmc.2015.09.051.

Banwell, M. G.; Buckler, J. N.; Jackson, C. J.; Lan, P.; Ma, X.; Matoušová, E.; Nugent, J. Devising New Syntheses of the Alkaloid Galanthamine, a Potent and Clinically Deployed Inhibitor of Acetylcholine Esterase; Elsevier, 2015; Vol. 11, pp 29-50.

Banwell, M. G.; Buckler, J. N.; Jackson, C. J.; Lan, P.; Ma, X.; Matoušová, E.; Nugent, J. Devising New Syntheses of the Alkaloid Galanthamine, a Potent and Clinically Deployed Inhibitor of Acetylcholine Esterase; Elsevier, 2015; Vol. 11, pp 29-50.

A. Downey, M.; Richter, C.; Pohl, R.; Mahrwald, R.; Hocek, M. Direct One-Pot Synthesis of Nucleosides from Unprotected or 5-O-Monoprotected D-Ribose. Organic Letters 2015, 17 (18), 4604-4607 DOI: 10.1021/acs.orglett.5b02332.

Ménová, P.; Dziuba, D.; Güixens-Gallardo, P.; Jurkiewicz, P.; Hof, M.; Hocek, M. Fluorescence Quenching in Oligonucleotides Containing 7-Substituted 7-Deazaguanine Bases Prepared by the Nicking Enzyme Amplification Reaction. Bioconjugate Chemistry 2015, 26 (2), 361-366 DOI: 10.1021/acs.bioconjchem.5b00006.

Mačková, M.; Boháčová, S.; Perlíková, P.; Slavětínská, L. Poštová; Hocek, M. Polymerase Synthesis and Restriction Enzyme Cleavage of DNA Containing 7-Substituted 7-Deazaguanine Nucleobases. ChemBioChem 2015, 16 (15), 2225-2236 DOI: 10.1002/cbic.201500315.

Popr, M.; Filippov, S. K.; Matushkin, N.; Dian, J.; Jindřich, J. Properties of cationic monosubstituted tetraalkylammonium cyclodextrin derivatives – their stability, complexation ability in solution or when deposited on solid anionic surface. Beilstein Journal of Organic Chemistry 2015, 11, 192-199 DOI: 10.3762/bjoc.11.20.

Murphy, B.; Šnajdr, I.; Machara, A.; Endoma-Arias, M. Ann A.; Stamatatos, T. C.; D. Cox, P.; Hudlicky, T. Conversion of Thebaine to Oripavine and Other Useful Intermediates for the Semisynthesis of Opiate-Derived Agents: Synthesis of Hydromorphone. Advanced Synthesis & Catalysis 2014, 356 (11-12), 2679-2687 DOI: 10.1002/adsc.201400445.

Murphy, B.; Šnajdr, I.; Machara, A.; Endoma-Arias, M. Ann A.; Stamatatos, T. C.; D. Cox, P.; Hudlicky, T. Conversion of Thebaine to Oripavine and Other Useful Intermediates for the Semisynthesis of Opiate-Derived Agents: Synthesis of Hydromorphone. Advanced Synthesis & Catalysis 2014, 356 (11-12), 2679-2687 DOI: 10.1002/adsc.201400445.

Motloch, P.; Valterová, I.; Kotora, M. Enantioselective Allylation of Thiophene-2-carbaldehyde: Formal Total Synthesis of Duloxetine. Advanced Synthesis & Catalysis 2014, 356 (1), 199-204 DOI: 10.1002/adsc.201300849.

Hanzlová, E.; Váňa, J.; Shaffer, C. J.; Roithová, J.; Martinů, T. Evidence for the Cyclic CN ₂ Carbene in the Gas Phase. Organic Letters 2014, 16 (20), 5482-5485 DOI: 10.1021/ol5027602.

Tumova, L.; Pombinho, A. R.; Vojtechova, M.; Stancikova, J.; Gradl, D.; Krausova, M.; Sloncova, E.; Horazna, M.; Kriz, V.; Machonova, O.; et al. Monensin inhibits canonical wnt signaling in human colorectal cancer cells and suppresses tumor growth in multiple intestinal neoplasia mice. Molecular cancer therapeutics 2014, 13 (4), 812-822 DOI: 10.1158/1535-7163.MCT-13-0625.

Mačková, M.; Pohl, R.; Hocek, M. Polymerase Synthesis of DNAs Bearing Vinyl Groups in the Major Groove and their Cleavage by Restriction Endonucleases. ChemBioChem 2014, 15 (15), 2306-2312 DOI: 10.1002/cbic.201402319.

Ceban, V.; Putaj, P.; Meazza, M.; Pitak, M. B.; Coles, S. J.; Vesely, J.; Rios, R. Synergistic catalysis: highly diastereoselective benzoxazole addition to Morita–Baylis–Hillman carbonates. Chemical Communications 2014, 50 (56), 7447 DOI: 10.1039/c4cc00728j.

Dhami, K.; Malyshev, D. A.; Ordoukhanian, P.; Kubelka, T.; Hocek, M.; Romesberg, F. E. Systematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabet. Nucleic Acids Research 2014, 42 (16), 10235-10244 DOI: 10.1093/nar/gku715.

Gülak, S.; Štěpánek, O.; Malberg, J.; Rad, B. Rezaei; Kotora, M.; Wolf, R.; von Wangelin, A. Jacobi. Highly chemoselective cobalt-catalyzed biaryl coupling reactions. Chem. Sci. 2013, 4 (2), 776-784 DOI: 10.1039/C2SC21667A.