Publications

Tichotová, L.; Matoušová, E.; Špulák, M.; Kuneš, J.; Votruba, I.; Buchta, V.; Pour, M. Synthesis and biological activity of desmethoxy analogues of coruscanone A. Bioorganic & Medicinal Chemistry Letters 2011, 21 (20), 6062-6066 DOI: 10.1016/j.bmcl.2011.08.059.

Tichý, M.; Pohl, R.; Tloušt’ová, E.; Weber, J.; Bahador, G.; Lee, Y. - J.; Hocek, M. Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido[4,5-b]indole ribonucleosides. Bioorganic & Medicinal Chemistry 2013, 21 (17), 5362-5372 DOI: 10.1016/j.bmc.2013.06.011.

Eignerová, B.; Sedlák, D.; Dračínský, M.; Bartůněk, P.; Kotora, M. Synthesis and Biochemical Characterization of a Series of 17α-Perfluoroalkylated Estradiols as Selective Ligands for Estrogen Receptor α. Journal of Medicinal Chemistry 2010, 53 (19), 6947-6953 DOI: 10.1021/jm100563h.

Tichý, M.; Pohl, R.; Xu, H. Ying; Chen, Y. - L.; Yokokawa, F.; Shi, P. - Y.; Hocek, M. Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides. Bioorganic & Medicinal Chemistry 2012, 20 (20), 6123-6133 DOI: 10.1016/j.bmc.2012.08.021.

Doleželová, E.; Džubák, P.; Gurská, S.; Hajdúch, M.; Hocek, M.; Krajczyk, A.; Milisavljević, N.; Perlíková, P.; Slavětínská, L. Poštová; Slapničková, M.; et al. Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides. ACS Infectious Diseases 2021, 7 (4), 917-926.

Doleželová, E.; Downey, A. Michael; Hocek, M.; Nguyen, V. Hai; Pohl, R.; Rožánková, S.; Slapničková, M.; Tichý, M.; Tloušťová, E.; Zíková, A. Synthesis and anti-trypanosomal activity of 3'-fluororibonucleosides derived from 7-deazapurine nucleosides. Bioorganic and Medicinal Chemistry Letters 2021, 40 (May 15 2021), nestránkováno.

Hessler, F.; Korotvička, A.; Nečas, D.; Valterová, I.; Kotora, M. Syntheses of a Flobufen Metabolite and Dapoxetine Based on Enantioselective Allylation of Aromatic Aldehydes: Syntheses of a Flobufen Metabolite and Dapoxetine. European Journal of Organic Chemistry 2014, 2014 (12), 2543-2548 DOI: 10.1002/ejoc.201301899.

Jindrich, J.; Cerny, M.; Trnka, T.; Budesinsky, M. Synhteses with Anhydro Sugars .39. The Synthesis of 4-O-Oligoethylene Glycol Derivatives of 1,6-Anhydro-beta-D-glycopyranos and Crown-ethers Formed by Their Intramolecular Cyclization. Collection of Czechoslovak Chemical Communications 1991, 56 (12), 2950-2963.

Ceban, V.; Putaj, P.; Meazza, M.; Pitak, M. B.; Coles, S. J.; Vesely, J.; Rios, R. Synergistic catalysis: highly diastereoselective benzoxazole addition to Morita–Baylis–Hillman carbonates. Chemical Communications 2014, 50 (56), 7447 DOI: 10.1039/c4cc00728j.

Benkovics, G.; Hodek, O.; Havlikova, M.; Bosakova, Z.; Coufal, P.; Malanga, M.; Fenyvesi, E.; Darcsi, A.; Beni, S.; Jindřich, J. Supramolecular structures based on regioisomers of cinnamyl-α-cyclodextrins – new media for capillary separation techniques. Beilstein Journal of Organic Chemistry 2016, 12, 97-109 DOI: 10.3762/bjoc.12.11.

Bojdys, M. J.; Briggs, M. E.; Jones, J. T. A.; Adams, D. J.; Chong, S. Y.; Schmidtmann, M.; Cooper, A. I. Supramolecular Engineering of Intrinsic and Extrinsic Porosity in Covalent Organic Cages. Journal of the American Chemical Society 2011, 133 (41), 16566-16571 DOI: 10.1021/ja2056374.

Kuprikova, N.; Ondruš, M.; Bednárová, L.; Fernández, M. Riopedre; Slavětínská, L. Poštová; Sýkorová, V.; Hocek, M. Superanionic DNA: enzymatic synthesis of hypermodified DNA bearing four different anionic substituents at all four nucleobases. Nucleic Acids Research 2023, 51 (21), 11428-11438.

Brynda, J.; Das, V.; Dvořanová, J.; Džubák, P.; Anwar, S. El; Fábry, M.; Grüner, B.; Gurska, S.; Hajdúch, M.; Havránek, M.; et al. Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX. European Journal of Medicinal Chemistry 2020, 200 (August), nestránkováno DOI: 10.1016/j.ejmech.2020.112460.

Nosek, V.; Míšek, J. Sulfinamide Crossover Reaction. Journal of Organic Chemistry 2024, 89 (11), 7927-7932.

Nauš, P.; Perlíková, P.; Bourderioux, A.; Pohl, R.; Slavětínská, L.; Votruba, I.; Bahador, G.; Birkuš, G.; Cihlář, T.; Hocek, M. Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2′-C-methylribonucleosides, 2′-deoxy-2′-fluoroarabinonucleosides, arabinonucleosides and 2′-deoxyribonucleosides. Bioorganic & Medicinal Chemistry 2012, 20 (17), 5202-5214 DOI: 10.1016/j.bmc.2012.07.003.

Mikušek, J.; Matouš, P.; Matoušová, E.; Janoušek, M.; Kuneš, J.; Pour, M. Substrate Control in the Gold(I)-Catalyzed Cyclization of β - Propargylamino Acrylic Esters and Further Transformations of the Resultant Dihydropyridines. Advanced Synthesis & Catalysis 2016, 358 (18), 2912-2922 DOI: 10.1002/adsc.201600412.

Císařová, I.; Hara, S.; Kotora, M.; Topolovčan, N.; Tošner, Z. A Study of Polarization and Directing Effects of Unsymmetrical Alkynes Using Regioselective Pd-Catalyzed Bromoallylation. European Journal of Organic Chemistry 2020, 2020 (2), 234-240 DOI: 10.1002/ejoc.201901476.

Navrátilová, K.; Řezanka, P.; Řezanka, M.; Sýkora, D.; Jindřich, J.; Král, V. The study of enantioselectivity of all regioisomers of mono-carboxymethyl-β-cyclodextrin used as chiral selectors in CE. Journal of Separation Science 2013, 36 (7), 1270–1274 DOI: 10.1002/jssc.201201144.

Bouřa, E.; Dejmek, M.; Chalupská, D.; Klíma, M.; Matoušová, M.; Mertlíková-Kaiserová, H.; Misehe, M.; Nencka, R.; Šála, M. Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold. Bioorganic and Medicinal Chemistry Letters 2022, 76 (November), nestránkováno.

Schimer, J.; Cígler, P.; Vesely, J.; Šašková, K. Grantz; Lepšík, M.; Brynda, J.; Řezáčová, P.; Kožíšek, M.; Císařová, I.; Oberwinkler, H.; et al. Structure-Aided Design of Novel Inhibitors of HIV Protease Based on a Benzodiazepine Scaffold. Journal of Medicinal Chemistry 2012, 55 (22), 10130-10135 DOI: 10.1021/jm301249q.

Hejdánek, J.; Hodek, J.; Konvalinka, J.; Kožíšek, M.; Machara, A.; Pachl, P.; Radilová, K.; Řezáčová, P.; Weber, J. Structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor. Antiviral Research 2021, 185 (January), nestránkováno.

Snášel, J.; Nauš, P.; Dostál, J.; Hnízda, A.; Fanfrlík, J.; Brynda, J.; Bourderioux, A.; Dušek, M.; Dvořáková, H.; Stolaříková, J.; et al. Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides. Journal of Medicinal Chemistry 2014, 57 (20), 8268-8279 DOI: 10.1021/jm500497v.

Baszczynski, O.; Cigáň, M.; Filo, J.; Prochazkova, E. Sterically-Controlled Self-Immolation in Phosphoramidate Linkers Triggered by Light. European Journal of Organic Chemistry 2020, 2020 (7), 897-906 DOI: 10.1002/ejoc.201901882.

Beier, P.; Janecký, L.; Klepetářová, B.; Markos, A.; Pohl, R. Stereoselective synthesis of (Z)-β-enamido fluorides from N-fluoroalkyl- and N-sulfonyl-1,2,3-triazoles. Organic Letters 2021, 23 (11), 4224-4227.

Markos, A.; Voltrova, S.; Motornov, V.; Tichy, D.; Klepetářová, B.; Beier, P. Stereoselective Synthesis of (Z)-beta-Enamido Triflates and Fluorosulfonates from N-Fluoroalkylated Triazoles. Chemistry-a European Journal 2019, 25 (32), 7640-7644 DOI: 10.1002/chem.201901632.