Publications

Kočovský, P.; Kuneš, J.; Kysilka, O.; Májek, M.; Maříková, J.; Matouš, P.; Pour, M.; Růžička, A. Reaction Outcome Critically Dependent on the Method of Workup: An Example from the Synthesis of 1-Isoquinolones. Journal of Organic Chemistry 2021, 86 (12), 8078-8088.

Prochazkova, E.; Navrátil, R.; Janeba, Z.; Roithová, J.; Baszczynski, O. Reactive cyclic intermediates in the ProTide prodrugs activation: trapping the elusive pentavalent phosphorane. Organic & Biomolecular Chemistry 2019, 17 (2), 315-320 DOI: 10.1039/c8ob02870b.

Jindřich, J.; Pitha, J.; Lindberg, B.; Seffers, P.; Harata, K. Regioselectivity of alkylation of cyclomaltoheptaose ([beta]-cyclodextrin) and synthesis of its mono-2-O-methyl, -ethyl, -allyl, and -propyl derivatives. Carbohydrate Research 1995, 266 (1), 75-80 DOI: 10.1016/0008-6215(94)00251-A.

Abdelsayed, M. M.; A. Chamberlin, R.; Chizzolini, F.; Kasireddy, S. Reddy; Luptak, A.; Míšek, J.; Passalacqua, L. F. M.; Rotstan, K. A. Regulation of mRNA translation by a photoriboswitch. eLife 2020, 9 (February 2020), nestránkováno DOI: 10.7554/eLife.51737.

Jindrich, J.; Pitha, J.; Lindberg, B. Separation of cyclodextrins and their derivatives by thin-layer and preparative column chromatography. Carbohydrate Research 1995, 275 (1), 1-7.

Dziuba, D.; Pospíšil, P.; Matyašovský, J.; Brynda, J.; Nachtigallová, D.; Rulíšek, L.; Pohl, R.; Hof, M.; Hocek, M. Solvatochromic fluorene-linked nucleoside and DNA as color-changing fluorescent probes for sensing interactions. Chem. Sci. 2016, 7 (9), 5775-5785 DOI: 10.1039/C6SC02548J.

Dziuba, D.; Pospíšil, P.; Matyašovský, J.; Brynda, J.; Nachtigallová, D.; Rulíšek, L.; Pohl, R.; Hof, M.; Hocek, M. Solvatochromic fluorene-linked nucleoside and DNA as color-changing fluorescent probes for sensing interactions. Chem. Sci. 2016, 7 (9), 5775-5785 DOI: 10.1039/C6SC02548J.

Machara, A.; Lux, V.; Kožíšek, M.; Šašková, K. Grantz; Štěpánek, O.; Kotora, M.; Parkan, K.; Pávová, M.; Glass, B.; Sehr, P.; et al. Specific Inhibitors of HIV Capsid Assembly Binding to the C-Terminal Domain of the Capsid Protein: Evaluation of 2-Arylquinazolines as Potential Antiviral Compounds. Journal of Medicinal Chemistry 2016, 59 (2), 545-558 DOI: 10.1021/acs.jmedchem.5b01089.

Machara, A.; Lux, V.; Kožíšek, M.; Šašková, K. Grantz; Štěpánek, O.; Kotora, M.; Parkan, K.; Pávová, M.; Glass, B.; Sehr, P.; et al. Specific Inhibitors of HIV Capsid Assembly Binding to the C-Terminal Domain of the Capsid Protein: Evaluation of 2-Arylquinazolines as Potential Antiviral Compounds. Journal of Medicinal Chemistry 2016, 59 (2), 545-558 DOI: 10.1021/acs.jmedchem.5b01089.

Prchalová, E.; Votruba, I.; Kotora, M. Sphingosine and clavaminol H derivatives bearing fluorinated chains and their cytotoxic activity. Journal of Fluorine Chemistry 2012, 141, 49-57 DOI: 10.1016/j.jfluchem.2012.06.005.

Ivancova, I.; Pohl, R.; Hubalek, M.; Hocek, M. Squaramate-Modified Nucleotides and DNA for Specific Cross-Linking with Lysine-Containing Peptides and Proteins. Angewandte Chemie-International Edition 2019, 58 (38), 13345-13348 DOI: 10.1002/anie.201906737.

Beier, P.; Janecký, L.; Klepetářová, B.; Markos, A.; Pohl, R. Stereoselective synthesis of (Z)-β-enamido fluorides from N-fluoroalkyl- and N-sulfonyl-1,2,3-triazoles. Organic Letters 2021, 23 (11), 4224-4227.

Baszczynski, O.; Cigáň, M.; Filo, J.; Prochazkova, E. Sterically-Controlled Self-Immolation in Phosphoramidate Linkers Triggered by Light. European Journal of Organic Chemistry 2020, 2020 (7), 897-906 DOI: 10.1002/ejoc.201901882.

Snášel, J.; Nauš, P.; Dostál, J.; Hnízda, A.; Fanfrlík, J.; Brynda, J.; Bourderioux, A.; Dušek, M.; Dvořáková, H.; Stolaříková, J.; et al. Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides. Journal of Medicinal Chemistry 2014, 57 (20), 8268-8279 DOI: 10.1021/jm500497v.

Snášel, J.; Nauš, P.; Dostál, J.; Hnízda, A.; Fanfrlík, J.; Brynda, J.; Bourderioux, A.; Dušek, M.; Dvořáková, H.; Stolaříková, J.; et al. Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides. Journal of Medicinal Chemistry 2014, 57 (20), 8268-8279 DOI: 10.1021/jm500497v.

Hejdánek, J.; Hodek, J.; Konvalinka, J.; Kožíšek, M.; Machara, A.; Pachl, P.; Radilová, K.; Řezáčová, P.; Weber, J. Structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor. Antiviral Research 2021, 185 (January), nestránkováno.

Mikušek, J.; Matouš, P.; Matoušová, E.; Janoušek, M.; Kuneš, J.; Pour, M. Substrate Control in the Gold(I)-Catalyzed Cyclization of β - Propargylamino Acrylic Esters and Further Transformations of the Resultant Dihydropyridines. Advanced Synthesis & Catalysis 2016, 358 (18), 2912-2922 DOI: 10.1002/adsc.201600412.

Nauš, P.; Perlíková, P.; Bourderioux, A.; Pohl, R.; Slavětínská, L.; Votruba, I.; Bahador, G.; Birkuš, G.; Cihlář, T.; Hocek, M. Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2′-C-methylribonucleosides, 2′-deoxy-2′-fluoroarabinonucleosides, arabinonucleosides and 2′-deoxyribonucleosides. Bioorganic & Medicinal Chemistry 2012, 20 (17), 5202-5214 DOI: 10.1016/j.bmc.2012.07.003.

Nauš, P.; Perlíková, P.; Bourderioux, A.; Pohl, R.; Slavětínská, L.; Votruba, I.; Bahador, G.; Birkuš, G.; Cihlář, T.; Hocek, M. Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2′-C-methylribonucleosides, 2′-deoxy-2′-fluoroarabinonucleosides, arabinonucleosides and 2′-deoxyribonucleosides. Bioorganic & Medicinal Chemistry 2012, 20 (17), 5202-5214 DOI: 10.1016/j.bmc.2012.07.003.

Brynda, J.; Das, V.; Dvořanová, J.; Džubák, P.; Anwar, S. El; Fábry, M.; Grüner, B.; Gurska, S.; Hajdúch, M.; Havránek, M.; et al. Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX. European Journal of Medicinal Chemistry 2020, 200 (August), nestránkováno DOI: 10.1016/j.ejmech.2020.112460.

Ceban, V.; Putaj, P.; Meazza, M.; Pitak, M. B.; Coles, S. J.; Vesely, J.; Rios, R. Synergistic catalysis: highly diastereoselective benzoxazole addition to Morita–Baylis–Hillman carbonates. Chemical Communications 2014, 50 (56), 7447 DOI: 10.1039/c4cc00728j.

Ceban, V.; Putaj, P.; Meazza, M.; Pitak, M. B.; Coles, S. J.; Vesely, J.; Rios, R. Synergistic catalysis: highly diastereoselective benzoxazole addition to Morita–Baylis–Hillman carbonates. Chemical Communications 2014, 50 (56), 7447 DOI: 10.1039/c4cc00728j.

Doleželová, E.; Downey, A. Michael; Hocek, M.; Nguyen, V. Hai; Pohl, R.; Rožánková, S.; Slapničková, M.; Tichý, M.; Tloušťová, E.; Zíková, A. Synthesis and anti-trypanosomal activity of 3'-fluororibonucleosides derived from 7-deazapurine nucleosides. Bioorganic and Medicinal Chemistry Letters 2021, 40 (May 15 2021), nestránkováno.

Doleželová, E.; Džubák, P.; Gurská, S.; Hajdúch, M.; Hocek, M.; Krajczyk, A.; Milisavljević, N.; Perlíková, P.; Slavětínská, L. Poštová; Slapničková, M.; et al. Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides. ACS Infectious Diseases 2021, 7 (4), 917-926.

Tichý, M.; Pohl, R.; Xu, H. Ying; Chen, Y. - L.; Yokokawa, F.; Shi, P. - Y.; Hocek, M. Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides. Bioorganic & Medicinal Chemistry 2012, 20 (20), 6123-6133 DOI: 10.1016/j.bmc.2012.08.021.