Publications

Perlíková, P.; Konečný, P.; Nauš, P.; Snášel, J.; Votruba, I.; Džubák, P.; Pichová, I.; Hajdúch, M.; Hocek, M. 6-Alkyl-, 6-aryl- or 6-hetaryl-7-deazapurine ribonucleosides as inhibitors of human or MTB adenosine kinase and potential antimycobacterial agents. MedChemComm 2013, 4 (11), 1497 DOI: 10.1039/c3md00232b.

Cahová, H.; Panattoni, A.; Kielkowski, P.; Fanfrlík, J.; Hocek, M. 5-Substituted Pyrimidine and 7-Substituted 7-Deazapurine dNTPs as Substrates for DNA Polymerases in Competitive Primer Extension in the Presence of Natural dNTPs. ACS Chemical Biology 2016, 11 (11), 3165-3171 DOI: 10.1021/acschembio.6b00714.

Janoušková, M.; Vaníková, Z.; Nici, F.; Boháčová, S.; Vitovska, D.; Šanderová, H.; Hocek, M.; Krásný, L. 5-(Hydroxymethyl) uracil and -cytosine as potential epigenetic marks enhancing or inhibiting transcription with bacterial RNA polymerase. Chemical Communications 2017, 53 (99), 13253-13255 DOI: 10.1039/c7cc08053k.

Drastík, M.; Holas, O.; Hroch, M.; Hutníková, M.; Kašpar, M.; Kudová, E.; Mičuda, S.; Pandey, A. V.; Pávek, P.; Smutný, T.; et al. 3 beta-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3 alpha-epimer by hepatic metabolism. Journal of Steroid Biochemistry and Molecular Biology 2020, 202 (September), nestránkováno DOI: 10.1016/j.jsbmb.2020.105702.

Matyašovský, J.; Perlíková, P.; Malnuit, V.; Pohl, R.; Hocek, M. 2-Substituted dATP Derivatives as Building Blocks for Polymerase-Catalyzed Synthesis of DNA Modified in the Minor Groove. Angewandte Chemie International Edition 2016, 55 (51), 15856-15859 DOI: 10.1002/anie.201609007.

Malnuit, V.; Slavětínská, L. Poštová; Nauš, P.; Džubák, P.; Hajdúch, M.; Stolaříková, J.; Snášel, J.; Pichová, I.; Hocek, M. 2-Substituted 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Inhibition of Adenosine Kinases, and Antimycobacterial Activity. ChemMedChem 2015, 10 (6), 1079-1093 DOI: 10.1002/cmdc.201500081.

Hocek, M.; Matyašovský, J. 2-Substituted 2 '-deoxyinosine 5 '-triphosphates as substrates for polymerase synthesis of minor-groove-modified DNA and effects on restriction endonuclease cleavage. Organic and Biomolecular Chemistry 2020, 18 (2), 255-262 DOI: 10.1039/c9ob02502b.

Brunderová, M.; Hocek, M.; Ivancova, I.; Krömer, M.; Slavětínská, L. Poštová. 2-Formyl-dATP as Substrate for Polymerase Synthesis of Reactive DNA Bearing an Aldehyde Group in the Minor Groove. ChemPlusChem 2020, 85 (6), 1164-1170 DOI: 10.1002/cplu.202000287.

Bojdys, M. J. 2D or not 2D-Layered Functional (C, N) Materials “Beyond Silicon and Graphene”. Macromolecular Chemistry and Physics 2016, 217 (2), 232-241 DOI: 10.1002/macp.201500312.

Matyašovský, J.; Pohl, R.; Hocek, M. 2-Allyl- and Propargylamino-dATPs for Site-Specific Enzymatic Introduction of a Single Modification in the Minor Groove of DNA. Chemistry-a European Journal 2018, 24 (56), 14938-14941 DOI: 10.1002/chem.201803973.

Matoušová, E.; Gyepes, R.; Císařová, I.; Kotora, M. [2+2+2]-Cyclotrimerization of 1-Cyclopropyl-1,6-diynes with Alkynes: Formation of Cyclopropylarenes. Advanced Synthesis & Catalysis 2016, 358 (2), 254-267 DOI: 10.1002/adsc.201500851.

Kaiser, R. P.; Hessler, F.; Mosinger, J.; Císařová, I.; Kotora, M. A [2+2+2]-Cyclotrimerization Approach to Selectively Substituted Fluorenes and Fluorenols, and Their Conversion to 9,9′-Spirobifluorenes. Chemistry - A European Journal 2015, 21 (39), 13577-13582 DOI: 10.1002/chem.201502370.

Kotora, M.; Hocek, M.; Turek, P.; Pohl, R.; Klepetářová, B.; Votruba, I.; Opekar, S. [2+2+2]-Cocyclotrimerization of 6-Alkynyl-7-benzylpurines with α,ω-Diynes. HETEROCYCLES 2010, 82 (1), 895 DOI: 10.3987/COM-10-S(E)56.

Luger, P.; Denner, L.; Cerny, M.; Jindřich, J.; Trnka, T. 16-Crown-5 derivative of 1,6-anhydro-[beta]-D-glucopyranose: structure of [1,6-anhydro-2,4-di-O-(3,6,9-trioxaundecane-1,11-diyl)-[beta]-D-glucopyranose]sodium tetraphenylborate. Acta Crystallographica, Section C: Structural Chemistry 1991, C47, 66-70 DOI: 10.1107/S0108270190007090.

Benýšek, J.; Krečmerová, M.; Matoušová, M.; Kaiserová, H. Mertlíkov; Otmar, M.; Pohl, R.; Pomeisl, K.; Pomeislová, A.; Slavětínská, L. Poštová; Rubešová, P. 1,2,4-Thiadiazole acyclic nucleoside phosphonates as inhibitors of cysteine dependent enzymes cathepsin K and GSK-3β. Bioorganic & Medicinal Chemistry 2021, 32 (February), nestránkováno.