Publications

Found 22 results
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Filters: Author is Hocek, Michal  [Clear All Filters]
2024
Brunderová, M.; Havlíček, V.; Matyašovský, J.; Pohl, R.; Slavětínská, L. Poštová; Krömer, M.; Hocek, M. Expedient production of site specifically nucleobase-labelled or hypermodified RNA with engineered thermophilic DNA polymerases (vol 15, 3054, 2023). Nature Communications 2024, 15 (1).
Brunderová, M.; Havlíček, V.; Matyašovský, J.; Pohl, R.; Slavětínská, L. Poštová; Krömer, M.; Hocek, M. Expedient production of site specifically nucleobase-labelled or hypermodified RNA with engineered thermophilic DNA polymerases. Nature Communications 2024, 15 (1).
Fleuti, M. Heidi; Quirante, T. Sanchez; Slavětínská, L. Poštová; Tloušťová, E.; Tichý, M.; Gurská, S.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and Biological Profiling of Quinolino-Fused 7-Deazapurine Nucleosides. ACS Omega 2024, 9 (18), 20557-20570.
2023
Jestřábová, I.; Slavětínská, L. Poštová; Hocek, M. Arylethynyl- or Alkynyl-Linked Pyrimidine and 7-Deazapurine 2′-Deoxyribonucleoside 3′-Phosphoramidites for Chemical Synthesis of Hypermodified Hydrophobic Oligonucleotides. ACS Omega 2023, 8 (42), 39447-39453.
Brunderová, M.; Krömer, M.; Vlková, M.; Hocek, M. Chloroacetamide-Modified Nucleotide and RNA for Bioconjugations and Cross-Linking with RNA-Binding Proteins. Angewandte Chemie - International Edition 2023, 62 (7).
Spampinato, A.; Kužmová, E.; Pohl, R.; Sýkorová, V.; Vrábel, M.; Kraus, T.; Hocek, M. trans-Cyclooctene- and Bicyclononyne-Linked Nucleotides for Click Modification of DNA with Fluorogenic Tetrazines and Live Cell Metabolic Labeling and Imaging. Bioconjugate Chemistry 2023, 34 (4), 772-780.
Ortiz, M.; Jauset-Rubio, M.; Trummer, O.; Foessl, I.; Kodr, D.; Acero, J. Lluís; Botero, M. Luz; Biggs, P.; Lenartowicz, D.; Trajanoska, K.; et al. Generic Platform for the Multiplexed Targeted Electrochemical Detection of Osteoporosis-Associated Single Nucleotide Polymorphisms Using Recombinase Polymerase Solid-Phase Primer Elongation and Ferrocene-Modified Nucleoside Triphosphates. ACS Central Science 2023, 9 (8), 1591-1602.
Kodr, D.; Kužmová, E.; Pohl, R.; Kraus, T.; Hocek, M. Lipid-linked nucleoside triphosphates for enzymatic synthesis of hydrophobic oligonucleotides with enhanced membrane anchoring efficiency. Chemical Science 2023, 14 (15), 4059-4069.
Kodr, D.; Ortiz, M.; Sýkorová, V.; Yenice, C. Pinar; Lesnikowski, Z. J.; O’Sullivan, C. K.; Hocek, M. Normalized Multipotential Redox Coding of DNA Bases for Determination of Total Nucleotide Composition. Analytical Chemistry 2023, 95 (34), 12586-12589.
Kuba, M.; Pohl, R.; Kraus, T.; Hocek, M. Nucleotides Bearing Red Viscosity-Sensitive Dimethoxy-Bodipy Fluorophore for Enzymatic Incorporation and DNA Labeling. Bioconjugate Chemistry 2023, 34 (1), 133-139.
Kuba, M.; Khoroshyy, P.; Lepšík, M.; Kužmová, E.; Kodr, D.; Kraus, T.; Hocek, M. Real-time Imaging of Nascent DNA in Live Cells by Monitoring the Fluorescence Lifetime of DNA-Incorporated Thiazole Orange-Modified Nucleotides. Angewandte Chemie - International Edition 2023, 62 (38).
Mulholland, C.; Jestřábová, I.; Sett, A.; Ondruš, M.; Sýkorová, V.; C. Manzanares, L.; Šimončík, O.; Muller, P.; Hocek, M. The selection of a hydrophobic 7-phenylbutyl-7-deazaadenine-modified DNA aptamer with high binding affinity for the Heat Shock Protein 70. Communications Chemistry 2023, 6 (1).
Kuprikova, N.; Ondruš, M.; Bednárová, L.; Fernández, M. Riopedre; Slavětínská, L. Poštová; Sýkorová, V.; Hocek, M. Superanionic DNA: enzymatic synthesis of hypermodified DNA bearing four different anionic substituents at all four nucleobases. Nucleic Acids Research 2023, 51 (21), 11428-11438.
Yang, C.; Tichý, M.; Slavětínská, L. Poštová; Vaiedelich, E.; Gurská, S.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and Biological Profiling of Benzofuro-Fused 7-Deazapurine Nucleosides. European Journal of Organic Chemistry 2023, 26 (44).
2022
Hocek, M.; Jauset-Rubio, M.; Kodr, D.; Ortiz, M.; O'Sullivan, C. Kathleen; Simonova, A. Solid-phase recombinase polymerase amplification using ferrocene-labelled dNTPs for electrochemical detection of single nucleotide polymorphisms. Biosensors and Bioelectronics 2022, 198 (February), nestránkováno.
Hocek, M.; Ondruš, M.; Sýkorová, V. Traceless enzymatic synthesis of monodispersed hypermodified oligodeoxyribonucleotide polymers from RNA templates. Chemical Communications 2022, 58 (80), 11248-11251.
2021
Bouřa, E.; Čížek, K.; Eyer, L.; Hocek, M.; Hodek, J.; Konkoľová, E.; Kozák, J.; Milisavljević, N.; Nencka, R.; Pohl, R.; et al. Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses. ACS Infectious Diseases 2021, 7 (2), 471-478.
Fojta, M.; Havran, L.; Hocek, M.; Kodr, D.; Lesnikowski, Z. J.; Ortiz, M.; O'Sullivan, C. Kathleen; Pohl, R.; Saftić, D. Pavlović; Simonova, A.; et al. Carborane- or Metallacarborane-Linked Nucleotides for Redox Labeling. Orthogonal Multipotential Coding of all Four DNA Bases for Electrochemical Analysis and Sequencing. Journal of the American Chemical Society 2021, 143 (18), 7124-7134.
Forster, R. J.; Hocek, M.; Magriñá, I.; Ortiz, M.; O'Sullivan, C. Kathleen; Simonova, A. Ferrocene-Containing DNA Monolayers: Influence of Electrostatics on the Electron Transfer Dynamics. Langmuir : the ACS journal of surfaces and colloids 2021, 37 (11), 3359-3369.
Gallardo, P. Güixens; Hocek, M.; Kraus, T.; Kuba, M.; Matyašovský, J.; Palágyi, A.; Pohl, R.; Tack, L. Nucleotides bearing aminophenyl- or aminonaphthyl-3-methoxychromone solvatochromic fluorophores for the enzymatic construction of DNA probes for the detection of protein-DNA binding. Organic and Biomolecular Chemistry 2021, 19 (45), 9966-9974.
Doleželová, E.; Downey, A. Michael; Hocek, M.; Nguyen, V. Hai; Pohl, R.; Rožánková, S.; Slapničková, M.; Tichý, M.; Tloušťová, E.; Zíková, A. Synthesis and anti-trypanosomal activity of 3'-fluororibonucleosides derived from 7-deazapurine nucleosides. Bioorganic and Medicinal Chemistry Letters 2021, 40 (May 15 2021), nestránkováno.
Doleželová, E.; Džubák, P.; Gurská, S.; Hajdúch, M.; Hocek, M.; Krajczyk, A.; Milisavljević, N.; Perlíková, P.; Slavětínská, L. Poštová; Slapničková, M.; et al. Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides. ACS Infectious Diseases 2021, 7 (4), 917-926.
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