Publications

Machara, A.; Pojarová, M.; Svoboda, J. Synthesis and Cycloaddition Reaction of 3-Vinylthieno[3,2-b][1]benzothiophene. Collection of Czechoslovak Chemical Communications 2007, 72 (7), 952-964 DOI: 10.1135/cccc20070952.

Tichotová, L.; Matoušová, E.; Špulák, M.; Kuneš, J.; Votruba, I.; Buchta, V.; Pour, M. Synthesis and biological activity of desmethoxy analogues of coruscanone A. Bioorganic & Medicinal Chemistry Letters 2011, 21 (20), 6062-6066 DOI: 10.1016/j.bmcl.2011.08.059.

Doleželová, E.; Džubák, P.; Gurská, S.; Hajdúch, M.; Hocek, M.; Krajczyk, A.; Milisavljević, N.; Perlíková, P.; Slavětínská, L. Poštová; Slapničková, M.; et al. Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides. ACS Infectious Diseases 2021, 7 (4), 917-926.

Ceban, V.; Putaj, P.; Meazza, M.; Pitak, M. B.; Coles, S. J.; Vesely, J.; Rios, R. Synergistic catalysis: highly diastereoselective benzoxazole addition to Morita–Baylis–Hillman carbonates. Chemical Communications 2014, 50 (56), 7447 DOI: 10.1039/c4cc00728j.

Benkovics, G.; Hodek, O.; Havlikova, M.; Bosakova, Z.; Coufal, P.; Malanga, M.; Fenyvesi, E.; Darcsi, A.; Beni, S.; Jindřich, J. Supramolecular structures based on regioisomers of cinnamyl-α-cyclodextrins – new media for capillary separation techniques. Beilstein Journal of Organic Chemistry 2016, 12, 97-109 DOI: 10.3762/bjoc.12.11.

Brynda, J.; Das, V.; Dvořanová, J.; Džubák, P.; Anwar, S. El; Fábry, M.; Grüner, B.; Gurska, S.; Hajdúch, M.; Havránek, M.; et al. Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX. European Journal of Medicinal Chemistry 2020, 200 (August), nestránkováno DOI: 10.1016/j.ejmech.2020.112460.

Brynda, J.; Das, V.; Dvořanová, J.; Džubák, P.; Anwar, S. El; Fábry, M.; Grüner, B.; Gurska, S.; Hajdúch, M.; Havránek, M.; et al. Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX. European Journal of Medicinal Chemistry 2020, 200 (August), nestránkováno DOI: 10.1016/j.ejmech.2020.112460.

Mikušek, J.; Matouš, P.; Matoušová, E.; Janoušek, M.; Kuneš, J.; Pour, M. Substrate Control in the Gold(I)-Catalyzed Cyclization of β - Propargylamino Acrylic Esters and Further Transformations of the Resultant Dihydropyridines. Advanced Synthesis & Catalysis 2016, 358 (18), 2912-2922 DOI: 10.1002/adsc.201600412.

Mikušek, J.; Matouš, P.; Matoušová, E.; Janoušek, M.; Kuneš, J.; Pour, M. Substrate Control in the Gold(I)-Catalyzed Cyclization of β - Propargylamino Acrylic Esters and Further Transformations of the Resultant Dihydropyridines. Advanced Synthesis & Catalysis 2016, 358 (18), 2912-2922 DOI: 10.1002/adsc.201600412.

Mikušek, J.; Matouš, P.; Matoušová, E.; Janoušek, M.; Kuneš, J.; Pour, M. Substrate Control in the Gold(I)-Catalyzed Cyclization of β - Propargylamino Acrylic Esters and Further Transformations of the Resultant Dihydropyridines. Advanced Synthesis & Catalysis 2016, 358 (18), 2912-2922 DOI: 10.1002/adsc.201600412.

Bouřa, E.; Dejmek, M.; Chalupská, D.; Klíma, M.; Matoušová, M.; Mertlíková-Kaiserová, H.; Misehe, M.; Nencka, R.; Šála, M. Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold. Bioorganic and Medicinal Chemistry Letters 2022, 76 (November), nestránkováno.

Bouřa, E.; Dejmek, M.; Chalupská, D.; Klíma, M.; Matoušová, M.; Mertlíková-Kaiserová, H.; Misehe, M.; Nencka, R.; Šála, M. Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold. Bioorganic and Medicinal Chemistry Letters 2022, 76 (November), nestránkováno.

Bouřa, E.; Dejmek, M.; Chalupská, D.; Klíma, M.; Matoušová, M.; Mertlíková-Kaiserová, H.; Misehe, M.; Nencka, R.; Šála, M. Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold. Bioorganic and Medicinal Chemistry Letters 2022, 76 (November), nestránkováno.

Hejdánek, J.; Hodek, J.; Konvalinka, J.; Kožíšek, M.; Machara, A.; Pachl, P.; Radilová, K.; Řezáčová, P.; Weber, J. Structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor. Antiviral Research 2021, 185 (January), nestránkováno.

Beier, P.; Janecký, L.; Klepetářová, B.; Markos, A.; Pohl, R. Stereoselective synthesis of (Z)-β-enamido fluorides from N-fluoroalkyl- and N-sulfonyl-1,2,3-triazoles. Organic Letters 2021, 23 (11), 4224-4227.

Markos, A.; Voltrova, S.; Motornov, V.; Tichy, D.; Klepetářová, B.; Beier, P. Stereoselective Synthesis of (Z)-beta-Enamido Triflates and Fluorosulfonates from N-Fluoroalkylated Triazoles. Chemistry-a European Journal 2019, 25 (32), 7640-7644 DOI: 10.1002/chem.201901632.

Markos, A.; Voltrova, S.; Motornov, V.; Tichy, D.; Klepetářová, B.; Beier, P. Stereoselective Synthesis of (Z)-beta-Enamido Triflates and Fluorosulfonates from N-Fluoroalkylated Triazoles. Chemistry-a European Journal 2019, 25 (32), 7640-7644 DOI: 10.1002/chem.201901632.

Machara, A.; Lux, V.; Kožíšek, M.; Šašková, K. Grantz; Štěpánek, O.; Kotora, M.; Parkan, K.; Pávová, M.; Glass, B.; Sehr, P.; et al. Specific Inhibitors of HIV Capsid Assembly Binding to the C-Terminal Domain of the Capsid Protein: Evaluation of 2-Arylquinazolines as Potential Antiviral Compounds. Journal of Medicinal Chemistry 2016, 59 (2), 545-558 DOI: 10.1021/acs.jmedchem.5b01089.

Machara, A.; Lux, V.; Kožíšek, M.; Šašková, K. Grantz; Štěpánek, O.; Kotora, M.; Parkan, K.; Pávová, M.; Glass, B.; Sehr, P.; et al. Specific Inhibitors of HIV Capsid Assembly Binding to the C-Terminal Domain of the Capsid Protein: Evaluation of 2-Arylquinazolines as Potential Antiviral Compounds. Journal of Medicinal Chemistry 2016, 59 (2), 545-558 DOI: 10.1021/acs.jmedchem.5b01089.

Dziuba, D.; Pospíšil, P.; Matyašovský, J.; Brynda, J.; Nachtigallová, D.; Rulíšek, L.; Pohl, R.; Hof, M.; Hocek, M. Solvatochromic fluorene-linked nucleoside and DNA as color-changing fluorescent probes for sensing interactions. Chem. Sci. 2016, 7 (9), 5775-5785 DOI: 10.1039/C6SC02548J.

Werner, L.; Machara, A.; Hudlicky, T. Short Chemoenzymatic Azide-Free Synthesis of Oseltamivir (Tamiflu): Approaching the Potential for Process Efficiency. Advanced Synthesis & Catalysis 2010, 352 (1), 195-200 DOI: 10.1002/adsc.200900844.

Werner, L.; Machara, A.; Sullivan, B.; Carrera, I.; Moser, M.; Adams, D. R.; Hudlicky, T.; Andraos, J. Several Generations of Chemoenzymatic Synthesis of Oseltamivir (Tamiflu): Evolution of Strategy, Quest for a Process-Quality Synthesis, and Evaluation of Efficiency Metrics. The Journal of Organic Chemistry 2011, 76 (24), 10050-10067 DOI: 10.1021/jo2018872.

Werner, L.; Machara, A.; Sullivan, B.; Carrera, I.; Moser, M.; Adams, D. R.; Hudlicky, T.; Andraos, J. Several Generations of Chemoenzymatic Synthesis of Oseltamivir (Tamiflu): Evolution of Strategy, Quest for a Process-Quality Synthesis, and Evaluation of Efficiency Metrics. The Journal of Organic Chemistry 2011, 76 (24), 10050-10067 DOI: 10.1021/jo2018872.

Ménová, P.; Raindlová, V.; Hocek, M. Scope and Limitations of the Nicking Enzyme Amplification Reaction for the Synthesis of Base-Modified Oligonucleotides and Primers for PCR. Bioconjugate Chemistry 2013, 24 (6), 1081-1093 DOI: 10.1021/bc400149q.

Albiñana, C. Berenguer; Hayward, J. J.; Hudlicky, T.; Machara, A. Reinvestigation of acetylation of 3,4-dihydroxybenzaldehyde and reconciliation of previously reported analytical data. Tetrahedron Letters 2016, 57 (9), 1019-1021 DOI: 10.1016/j.tetlet.2016.01.075.