Publications

Found 321 results
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2018
Ghosh, K.; Perlíková, P.; Havlicek, V.; Yang, C.; Pohl, R.; Tloušťová, E.; Hodek, J.; Gurska, S.; Džubák, P.; Hajdúch, M.; et al. Isomeric Naphtho-Fused 7-Deazapurine Nucleosides and Nucleotides: Synthesis, Biological Activity, Photophysical Properties and Enzymatic Incorporation to Nucleic Acids. European Journal of Organic Chemistry 2018, No. 37, 5092-5108 DOI: 10.1002/ejoc.201800165.
Krömer, M.; Bartova, K.; Raindlová, V.; Hocek, M. Synthesis of Dihydroxyalkynyl and Dihydroxyalkyl Nucleotides as Building Blocks or Precursors for Introduction of Diol or Aldehyde Groups to DNA for Bioconjugations. Chemistry-a European Journal 2018, 24 (46), 11890-11894 DOI: 10.1002/chem.201802282.
2017
Janoušková, M.; Vaníková, Z.; Nici, F.; Boháčová, S.; Vitovska, D.; Šanderová, H.; Hocek, M.; Krásný, L. 5-(Hydroxymethyl) uracil and -cytosine as potential epigenetic marks enhancing or inhibiting transcription with bacterial RNA polymerase. Chemical Communications 2017, 53 (99), 13253-13255 DOI: 10.1039/c7cc08053k.
Kamlar, M.; Císařová, I.; Hybelbauerová, S.; Vesely, J. Asymmetric Allylic Amination of Morita-Baylis-Hillman Carbonates with Silylated tert-Butylhydroxycarbamate Derivatives. European Journal of Organic Chemistry 2017, No. 14, 1926-1930 DOI: 10.1002/ejoc.201700222.
Balintová, J.; Simonova, A.; Bialek-Pietras, M.; Olejniczak, A.; Lesnikowski, Z. J.; Hocek, M. Carborane-linked 2 '-deoxyuridine 5 '-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA. Bioorganic & Medicinal Chemistry Letters 2017, 27 (21), 4786-4788 DOI: 10.1016/j.bmcl.2017.09.064.
Urban, M.; Franc, M.; Hofmanova, M.; Císařová, I.; Veselý, J. The enantioselective addition of 1-fluoro-1-nitro (phenylsulfonyl) methane to isatin-derived ketimines. Organic & Biomolecular Chemistry 2017, 15 (43), 9071-9076 DOI: 10.1039/c7ob02408h.
Trautner, S.; Jašík, J.; Parigger, C. G.; Pedarnig, J. D.; Spendelhofer, W.; Lackner, J.; Veis, P.; Heitz, J. Laser-induced optical breakdown spectroscopy of polymer materials based on evaluation of molecular emission bands. Spectrochimica Acta Part a-Molecular and Biomolecular Spectroscopy 2017, 174, 331-338 DOI: 10.1016/j.saa.2016.11.045.
Trautner, S.; Jašík, J.; Parigger, C. G.; Pedarnig, J. D.; Spendelhofer, W.; Lackner, J.; Veis, P.; Heitz, J. Laser-induced optical breakdown spectroscopy of polymer materials based on evaluation of molecular emission bands (vol 174, pg 331, 2017). Spectrochimica Acta Part a-Molecular and Biomolecular Spectroscopy 2017, 179, 73-73 DOI: 10.1016/j.saa.2017.02.016.
Váňa, J.; Lang, J.; Soltesova, M.; Hanusek, J.; Růžička, A.; Sedlák, M.; Roithová, J. The role of trinuclear species in a palladium acetate/trifluoroacetic acid catalytic system. Dalton Transactions 2017, 46 (46), 16269-16275 DOI: 10.1039/c7dt03832a.
A. Downey, M.; Pohl, R.; Roithová, J.; Hocek, M. Synthesis of Nucleosides through Direct Glycosylation of Nucleobases with 5-O-Monoprotected or 5-Modified Ribose: Improved Protocol, Scope, and Mechanism. Chemistry-a European Journal 2017, 23 (16), 3910-3917 DOI: 10.1002/chem.201604955.
Schwarz, D.; Kochergin, Y. S.; Acharjya, A.; Ichangi, A.; Opanasenko, M. V.; Cejka, J.; Lappan, U.; Arki, P.; He, J.; Schmidt, J.; et al. Tailored Band Gaps in Sulfur- and Nitrogen-Containing Porous Donor-Acceptor Polymers. Chemistry-a European Journal 2017, 23 (53), 13023-13027 DOI: 10.1002/chem.201703332.
Schwarz, D.; Noda, Y.; Klouda, J.; Schwarzova-Peckova, K.; Tarabek, J.; Rybacek, J.; Janousek, J.; Simon, F.; Opanasenko, M. V.; Cejka, J.; et al. Twinned Growth of Metal-Free, Triazine-Based Photocatalyst Films as Mixed-Dimensional (2D/3D) van der Waals Heterostructures. Advanced Materials 2017, 29 (40), 1703399 DOI: 10.1002/adma.201703399.
2016
Matyašovský, J.; Perlíková, P.; Malnuit, V.; Pohl, R.; Hocek, M. 2-Substituted dATP Derivatives as Building Blocks for Polymerase-Catalyzed Synthesis of DNA Modified in the Minor Groove. Angewandte Chemie International Edition 2016, 55 (51), 15856-15859 DOI: 10.1002/anie.201609007.
Cahová, H.; Panattoni, A.; Kielkowski, P.; Fanfrlík, J.; Hocek, M. 5-Substituted Pyrimidine and 7-Substituted 7-Deazapurine dNTPs as Substrates for DNA Polymerases in Competitive Primer Extension in the Presence of Natural dNTPs. ACS Chemical Biology 2016, 11 (11), 3165-3171 DOI: 10.1021/acschembio.6b00714.
Bosáková, A.; Perlíková, P.; Tichý, M.; Pohl, R.; Hocek, M. 6-Aryl-4-amino-pyrimido[4,5-b]indole 2′-deoxyribonucleoside triphosphates (benzo-fused 7-deaza-dATP analogues): Synthesis, fluorescent properties, enzymatic incorporation into DNA and DNA-protein binding study. Bioorganic & Medicinal Chemistry 2016, 24 (19), 4528-4535 DOI: 10.1016/j.bmc.2016.07.054.
Perlikova, P.; Rylova, G.; Naus, P.; Elbert, T.; Tloustova, E.; Bourderioux, A.; Slavetinska, L. P.; Motyka, K.; Dolezal, D.; Znojek, P.; et al. 7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action. Molecular Cancer Therapeutics 2016, 15 (5), 922-937 DOI: 10.1158/1535-7163.MCT-14-0933.
Perlikova, P.; Rylova, G.; Naus, P.; Elbert, T.; Tloustova, E.; Bourderioux, A.; Slavetinska, L. P.; Motyka, K.; Dolezal, D.; Znojek, P.; et al. 7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action. Molecular Cancer Therapeutics 2016, 15 (5), 922-937 DOI: 10.1158/1535-7163.MCT-14-0933.
Perlikova, P.; Rylova, G.; Naus, P.; Elbert, T.; Tloustova, E.; Bourderioux, A.; Slavetinska, L. P.; Motyka, K.; Dolezal, D.; Znojek, P.; et al. 7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action. Molecular Cancer Therapeutics 2016, 15 (5), 922-937 DOI: 10.1158/1535-7163.MCT-14-0933.
Perlikova, P.; Rylova, G.; Naus, P.; Elbert, T.; Tloustova, E.; Bourderioux, A.; Slavetinska, L. P.; Motyka, K.; Dolezal, D.; Znojek, P.; et al. 7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action. Molecular Cancer Therapeutics 2016, 15 (5), 922-937 DOI: 10.1158/1535-7163.MCT-14-0933.
Slavíčková, M.; Pohl, R.; Hocek, M. Additions of Thiols to 7-Vinyl-7-deazaadenine Nucleosides and Nucleotides. Synthesis of Hydrophobic Derivatives of 2′-Deoxyadenosine, dATP and DNA. The Journal of Organic Chemistry 2016, 81 (22), 11115-11125 DOI: 10.1021/acs.joc.6b02098.
Olszewska, A.; Pohl, R.; Brázdová, M.; Fojta, M.; Hocek, M. Chloroacetamide-Linked Nucleotides and DNA for Cross-Linking with Peptides and Proteins. Bioconjugate Chemistry 2016, 27 (9), 2089-2094 DOI: 10.1021/acs.bioconjchem.6b00342.
Botha, F.; Slavíčková, M.; Pohl, R.; Hocek, M. Copper-mediated arylsulfanylations and arylselanylations of pyrimidine or 7-deazapurine nucleosides and nucleotides. Org. Biomol. Chem. 2016, 14 (42), 10018-10022 DOI: 10.1039/C6OB01917J.
Sabat, N.; Slavětínská, L. Poštová; Klepetářová, B.; Hocek, M. C–H Phosphonation of Pyrrolopyrimidines: Synthesis of Substituted 7- and 9-Deazapurine-8-phosphonate Derivatives. The Journal of Organic Chemistry 2016, 81 (19), 9507-9514 DOI: 10.1021/acs.joc.6b01970.
Machara, A.; Endoma-Arias, M. Ann A.; Císařová, I.; D. Cox, P.; Hudlicky, T. Direct Synthesis of Noroxymorph­one from Thebaine: Unusual Ce IV Oxidation of a Methoxydiene-Iron Complex to an Enone-γ-Nitrate. European Journal of Organic Chemistry 2016, 2016 (8), 1500-1503 DOI: 10.1002/ejoc.201600153.
Kielkowski, P.; Cahová, H.; Pohl, R.; Hocek, M. Flexible double-headed cytosine-linked 2′-deoxycytidine nucleotides. Synthesis, polymerase incorporation to DNA and interaction with DNA methyltransferases. Bioorganic & Medicinal Chemistry 2016, 24 (6), 1268-1276 DOI: 10.1016/j.bmc.2016.01.057.
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