Publications

Arbon, D.; Mach, J.; Čadková, A.; Šipková, A.; Stursa, J.; Klanicová, K.; Machado, M.; Ganter, M.; Levytska, V.; Sojka, D.; et al. Chelation of Mitochondrial Iron as an Antiparasitic Strategy. ACS Infectious Diseases 2024, 10 (2), 676-687.

Kocek, H.; Chalupská, D.; Dejmek, M.; Dvořáková, A.; Zgarbová, M.; Šála, M.; Chalupský, K.; Krafčíková, P.; Otava, T.; Drexler, M.; et al. Discovery of highly potent SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5′-carboxamides. RSC Medicinal Chemistry 2024, nestránkováno.

Kočková, O.; Kasal, P.; Zelený, J.; Walterova, Z.; Vlčková, V.; Jindřich, J. Effect of Counterions on the Soft Ionization Mass Spectra of Analytes with Multiple Permanent Charges. Analytical Chemistry 2024, 96 (18), 6940-6946.

Nomura, K.; Mancuso, R.; Cai, Z.; Dagorne, S.; Eisen, M. S.; Gonsalvi, L.; Kotora, M.; Lee, B. Yeoul; Liu, S.; Martins, L. Margarida; et al. Exclusive Papers of the Editorial Board Members and Topical Advisory Panel Members of Catalysts in Section "Catalysis in Organic and Polymer Chemistry". Catalysts 2024, 14 (7).

Foppiani, J. A.; Weidman, A.; Alvarez, A. Hernandez; Valentine, L.; Bustos, V. P.; Galinaud, C.; Hrdina, R.; Hrdina, R.; Musil, Z.; Lee, B. T.; et al. A Meta-Analysis of the Mortality and the Prevalence of Burn Complications in Western Populations. Journal of Burn Care & Research 2024, 45 (4), 932-944.

Hadzima, M.; Faucher, F. F.; Blažková, K.; Yim, J. J.; Guerra, M.; Chen, S.; Woods, E. C.; Park, K. Wan; Šácha, P.; Šubr, V.; et al. Polymer-Tethered Quenched Fluorescent Probes for Enhanced Imaging of Tumor-Associated Proteases. ACS Sensors 2024, 9 (7), 3720-3729.

Novotná, K.; Tenora, L.; Prchalová, E.; Paule, J.; Alt, J.; Veeravalli, V.; Lam, J.; Wu, Y.; Šnajdr, I.; Gori, S.; et al. Discovery of tert-Butyl Ester Based 6-Diazo-5-oxo-l-norleucine Prodrugs for Enhanced Metabolic Stability and Tumor Delivery. Journal of Medicinal Chemistry 2023, 66 (22), 15493-15510.

Novotná, K.; Thomas, A. G.; Štěpánek, O.; Murphy, B.; Hin, N.; Skácel, J.; Mueller, L.; Tenora, L.; Pal, A.; Alt, J.; et al. Neutral sphingomyelinase 2 inhibitors based on the pyrazolo[1,5-a] scaffold. European Journal of Medicinal Chemistry 2023, 259 (November).

Štefek, M.; Chalupská, D.; Chalupský, K.; Zgarbová, M.; Dvořáková, A.; Krafčíková, P.; Li, A. Shi Ming; Šála, M.; Dejmek, M.; Otava, T.; et al. Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors. ACS Omega 2023, 8 (30), 27410-27418.

Břehová, P.; Česnek, M.; Dračínský, M.; Chaloupecká, E.; Janeba, Z.; Mertlíková-Kaiserová, H.; Skácel, J.; Soto-Velasquez, M. P.; Tloušťová, E.; Watts, V. J. Acyclic nucleoside phosphonates with 2-aminothiazole base as inhibitors of bacterial and mammalian adenylate cyclases. European Journal of Medicinal Chemistry 2021, 222 (October 15 2021), nestránkováno.

Bouřa, E.; Čížek, K.; Eyer, L.; Hocek, M.; Hodek, J.; Konkoľová, E.; Kozák, J.; Milisavljević, N.; Nencka, R.; Pohl, R.; et al. Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses. ACS Infectious Diseases 2021, 7 (2), 471-478.

Baszczyňski, O.; Dračínský, M.; Dvořáková, A.; Hodek, J.; Chalupský, K.; Janeba, Z.; Kalčic, F.; Kaiserová, H. Mertlíkov; Strmeň, T.; Šebestík, J.; et al. Discovery of Modified Amidate (ProTide) Prodrugs of Tenofovir with Enhanced Antiviral Properties. Journal of Medicinal Chemistry 2021, 64 (22), 16425-16449.

Hejdánek, J.; Hodek, J.; Konvalinka, J.; Kožíšek, M.; Machara, A.; Pachl, P.; Radilová, K.; Řezáčová, P.; Weber, J. Structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor. Antiviral Research 2021, 185 (January), nestránkováno.

Albiñana, C. Berenguer; Brynda, J.; Fanfrlík, J.; Flieger, M.; Hodek, J.; Karlukova, E.; Konvalinka, J.; Kožíšek, M.; Machara, A.; Majer, P.; et al. Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors. European Journal of Medicinal Chemistry 2020, 208 (December), nestránkováno DOI: 10.1016/j.ejmech.2020.112754.

Nauš, P.; Caletková, O.; Perlíková, P.; Slavětínská, L. Poštová; Tloušťová, E.; Hodek, J.; Weber, J.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides. Bioorganic & Medicinal Chemistry 2015, 23 (23), 7422-7438 DOI: 10.1016/j.bmc.2015.10.040.

Katekomol, P.; Roeser, J.; Bojdys, M.; Weber, J.; Thomas, A. Covalent Triazine Frameworks Prepared from 1,3,5-Tricyanobenzene. Chemistry of Materials 2013, 25 (9), 1542-1548 DOI: 10.1021/cm303751n.

Gülak, S.; Štěpánek, O.; Malberg, J.; Rad, B. Rezaei; Kotora, M.; Wolf, R.; von Wangelin, A. Jacobi. Highly chemoselective cobalt-catalyzed biaryl coupling reactions. Chem. Sci. 2013, 4 (2), 776-784 DOI: 10.1039/C2SC21667A.

Tichý, M.; Pohl, R.; Tloušt’ová, E.; Weber, J.; Bahador, G.; Lee, Y. - J.; Hocek, M. Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido[4,5-b]indole ribonucleosides. Bioorganic & Medicinal Chemistry 2013, 21 (17), 5362-5372 DOI: 10.1016/j.bmc.2013.06.011.

Machara, A.; Werner, L.; Endoma-Arias, M. Ann; D. Cox, P.; Hudlicky, T. Improved Synthesis of Buprenorphine from Thebaine and/or Oripavine via Palladium-Catalyzed N-Demethylation/Acylation and/or Concomitant O-Demethylation. Advanced Synthesis & Catalysis 2012, 354 (4), 613-626 DOI: 10.1002/adsc.201100807.

Werner, L.; Wernerova, M.; Machara, A.; Endoma-Arias, M. Ann; Duchek, J.; Adams, D. R.; D. Cox, P.; Hudlicky, T. Unexpected N -Demethylation of Oxymorphone and Oxycodone N -Oxides Mediated by the Burgess Reagent: Direct Synthesis of Naltrexone, Naloxone, and Other Antagonists from Oxymorphone. Advanced Synthesis & Catalysis 2012, 354 (14-15), 2706-2712 DOI: 10.1002/adsc.201200676.

Werner, L.; Wernerova, M.; Machara, A.; Endoma-Arias, M. Ann; Duchek, J.; Adams, D. R.; D. Cox, P.; Hudlicky, T. Unexpected N -Demethylation of Oxymorphone and Oxycodone N -Oxides Mediated by the Burgess Reagent: Direct Synthesis of Naltrexone, Naloxone, and Other Antagonists from Oxymorphone. Advanced Synthesis & Catalysis 2012, 354 (14-15), 2706-2712 DOI: 10.1002/adsc.201200676.

Nakanishi, T.; Weber, J.; Bojdys, M. J.; Thomas, A. Polymeric Frameworks: Toward Porous Semiconductors; John Wiley & Sons, Inc.: Hoboken, NJ, USA, 2011; pp 119-154.

Werner, L.; Machara, A.; Sullivan, B.; Carrera, I.; Moser, M.; Adams, D. R.; Hudlicky, T.; Andraos, J. Several Generations of Chemoenzymatic Synthesis of Oseltamivir (Tamiflu): Evolution of Strategy, Quest for a Process-Quality Synthesis, and Evaluation of Efficiency Metrics. The Journal of Organic Chemistry 2011, 76 (24), 10050-10067 DOI: 10.1021/jo2018872.

Werner, L.; Machara, A.; Adams, D. R.; D. Cox, P.; Hudlicky, T. Synthesis of Buprenorphine from Oripavine via N-Demethylation of Oripavine Quaternary Salts. The Journal of Organic Chemistry 2011, 76 (11), 4628-4634 DOI: 10.1021/jo200567n.

Bojdys, M. J.; Wohlgemuth, S. A.; Thomas, A.; Antonietti, M. Ionothermal Route to Layered Two-Dimensional Polymer-Frameworks Based on Heptazine Linkers. Macromolecules 2010, 43 (16), 6639-6645 DOI: 10.1021/ma101008c.