Publications

Found 184 results
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2015
Topolovčan, N.; Panov, I.; Kotora, M. Reaction of Bicyclic Zirconacyclopentenes with Aldehydes and a Potential Pathway to Condensed 5-7-6(Ar) Ring Systems: Reaction of Bicyclic Zirconacyclopentenes with Aldehydes. European Journal of Organic Chemistry 2015, 2015 (13), 2868-2878 DOI: 10.1002/ejoc.201500248.
Nauš, P.; Caletková, O.; Perlíková, P.; Slavětínská, L. Poštová; Tloušťová, E.; Hodek, J.; Weber, J.; Džubák, P.; Hajdúch, M.; Hocek, M. Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides. Bioorganic & Medicinal Chemistry 2015, 23 (23), 7422-7438 DOI: 10.1016/j.bmc.2015.10.040.
2016
Matyašovský, J.; Perlíková, P.; Malnuit, V.; Pohl, R.; Hocek, M. 2-Substituted dATP Derivatives as Building Blocks for Polymerase-Catalyzed Synthesis of DNA Modified in the Minor Groove. Angewandte Chemie International Edition 2016, 55 (51), 15856-15859 DOI: 10.1002/anie.201609007.
Matyašovský, J.; Perlíková, P.; Malnuit, V.; Pohl, R.; Hocek, M. 2-Substituted dATP Derivatives as Building Blocks for Polymerase-Catalyzed Synthesis of DNA Modified in the Minor Groove. Angewandte Chemie International Edition 2016, 55 (51), 15856-15859 DOI: 10.1002/anie.201609007.
Cahová, H.; Panattoni, A.; Kielkowski, P.; Fanfrlík, J.; Hocek, M. 5-Substituted Pyrimidine and 7-Substituted 7-Deazapurine dNTPs as Substrates for DNA Polymerases in Competitive Primer Extension in the Presence of Natural dNTPs. ACS Chemical Biology 2016, 11 (11), 3165-3171 DOI: 10.1021/acschembio.6b00714.
Bosáková, A.; Perlíková, P.; Tichý, M.; Pohl, R.; Hocek, M. 6-Aryl-4-amino-pyrimido[4,5-b]indole 2′-deoxyribonucleoside triphosphates (benzo-fused 7-deaza-dATP analogues): Synthesis, fluorescent properties, enzymatic incorporation into DNA and DNA-protein binding study. Bioorganic & Medicinal Chemistry 2016, 24 (19), 4528-4535 DOI: 10.1016/j.bmc.2016.07.054.
Bosáková, A.; Perlíková, P.; Tichý, M.; Pohl, R.; Hocek, M. 6-Aryl-4-amino-pyrimido[4,5-b]indole 2′-deoxyribonucleoside triphosphates (benzo-fused 7-deaza-dATP analogues): Synthesis, fluorescent properties, enzymatic incorporation into DNA and DNA-protein binding study. Bioorganic & Medicinal Chemistry 2016, 24 (19), 4528-4535 DOI: 10.1016/j.bmc.2016.07.054.
Perlikova, P.; Rylova, G.; Naus, P.; Elbert, T.; Tloustova, E.; Bourderioux, A.; Slavetinska, L. P.; Motyka, K.; Dolezal, D.; Znojek, P.; et al. 7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action. Molecular Cancer Therapeutics 2016, 15 (5), 922-937 DOI: 10.1158/1535-7163.MCT-14-0933.
Slavíčková, M.; Pohl, R.; Hocek, M. Additions of Thiols to 7-Vinyl-7-deazaadenine Nucleosides and Nucleotides. Synthesis of Hydrophobic Derivatives of 2′-Deoxyadenosine, dATP and DNA. The Journal of Organic Chemistry 2016, 81 (22), 11115-11125 DOI: 10.1021/acs.joc.6b02098.
Topolovčan, N.; Panov, I.; Kotora, M. Bisallylation of Zirconacyclopentenes and Ring-Closing Metathesis: A Route to Eight-Membered-Ring Compounds. Synlett 2016, 27 (03), 432-436 DOI: 10.1055/s-0035-1560587.
Pickard, C. J.; Salamat, A.; Bojdys, M. J.; Needs, R. J.; McMillan, P. F. Carbon nitride frameworks and dense crystalline polymorphs. Physical Review B 2016, 94 (9) DOI: 10.1103/PhysRevB.94.094104.
Olszewska, A.; Pohl, R.; Brázdová, M.; Fojta, M.; Hocek, M. Chloroacetamide-Linked Nucleotides and DNA for Cross-Linking with Peptides and Proteins. Bioconjugate Chemistry 2016, 27 (9), 2089-2094 DOI: 10.1021/acs.bioconjchem.6b00342.
Kučerová, G.; Kalíková, K.; Procházková, H.; Popr, M.; Jindřich, J.; Coufal, P.; Tesařová, E. Chromatographic Characterization of a New Cationic β-CD Based Stationary Phase Prepared by Dynamic Coating. Chromatographia 2016, 79 (9-10), 529-536 DOI: 10.1007/s10337-016-3050-z.
Kučerová, G.; Kalíková, K.; Procházková, H.; Popr, M.; Jindřich, J.; Coufal, P.; Tesařová, E. Chromatographic Characterization of a New Cationic β-CD Based Stationary Phase Prepared by Dynamic Coating. Chromatographia 2016, 79 (9-10), 529-536 DOI: 10.1007/s10337-016-3050-z.
Botha, F.; Slavíčková, M.; Pohl, R.; Hocek, M. Copper-mediated arylsulfanylations and arylselanylations of pyrimidine or 7-deazapurine nucleosides and nucleotides. Org. Biomol. Chem. 2016, 14 (42), 10018-10022 DOI: 10.1039/C6OB01917J.
Kielkowski, P.; Cahová, H.; Pohl, R.; Hocek, M. Flexible double-headed cytosine-linked 2′-deoxycytidine nucleotides. Synthesis, polymerase incorporation to DNA and interaction with DNA methyltransferases. Bioorganic & Medicinal Chemistry 2016, 24 (6), 1268-1276 DOI: 10.1016/j.bmc.2016.01.057.
Raindlová, V.; Janoušková, M.; Slavíčková, M.; Perlíková, P.; Boháčová, S.; Milisavljevič, N.; Šanderová, H.; Benda, M.; Barvík, I.; Krásný, L.; et al. Influence of major-groove chemical modifications of DNA on transcription by bacterial RNA polymerases. Nucleic Acids Research 2016, 44 (7), 3000-3012 DOI: 10.1093/nar/gkw171.
Güixens-Gallardo, P.; Hocek, M.; Perlíková, P. Inhibition of non-templated nucleotide addition by DNA polymerases in primer extension using twisted intercalating nucleic acid modified templates. Bioorganic & Medicinal Chemistry Letters 2016, 26 (2), 288-291 DOI: 10.1016/j.bmcl.2015.12.034.
Albiñana, C. Berenguer; Machara, A.; Řezáčová, P.; Pachl, P.; Konvalinka, J.; Kožíšek, M. Kinetic, thermodynamic and structural analysis of tamiphosphor binding to neuraminidase of H1N1 (2009) pandemic influenza. European Journal of Medicinal Chemistry 2016, 121, 100-109 DOI: 10.1016/j.ejmech.2016.05.016.
Dziuba, D.; Pospíšil, P.; Matyašovský, J.; Brynda, J.; Nachtigallová, D.; Rulíšek, L.; Pohl, R.; Hof, M.; Hocek, M. Solvatochromic fluorene-linked nucleoside and DNA as color-changing fluorescent probes for sensing interactions. Chem. Sci. 2016, 7 (9), 5775-5785 DOI: 10.1039/C6SC02548J.
Dziuba, D.; Pospíšil, P.; Matyašovský, J.; Brynda, J.; Nachtigallová, D.; Rulíšek, L.; Pohl, R.; Hof, M.; Hocek, M. Solvatochromic fluorene-linked nucleoside and DNA as color-changing fluorescent probes for sensing interactions. Chem. Sci. 2016, 7 (9), 5775-5785 DOI: 10.1039/C6SC02548J.
Machara, A.; Lux, V.; Kožíšek, M.; Šašková, K. Grantz; Štěpánek, O.; Kotora, M.; Parkan, K.; Pávová, M.; Glass, B.; Sehr, P.; et al. Specific Inhibitors of HIV Capsid Assembly Binding to the C-Terminal Domain of the Capsid Protein: Evaluation of 2-Arylquinazolines as Potential Antiviral Compounds. Journal of Medicinal Chemistry 2016, 59 (2), 545-558 DOI: 10.1021/acs.jmedchem.5b01089.
Machara, A.; Lux, V.; Kožíšek, M.; Šašková, K. Grantz; Štěpánek, O.; Kotora, M.; Parkan, K.; Pávová, M.; Glass, B.; Sehr, P.; et al. Specific Inhibitors of HIV Capsid Assembly Binding to the C-Terminal Domain of the Capsid Protein: Evaluation of 2-Arylquinazolines as Potential Antiviral Compounds. Journal of Medicinal Chemistry 2016, 59 (2), 545-558 DOI: 10.1021/acs.jmedchem.5b01089.
Mikušek, J.; Matouš, P.; Matoušová, E.; Janoušek, M.; Kuneš, J.; Pour, M. Substrate Control in the Gold(I)-Catalyzed Cyclization of β - Propargylamino Acrylic Esters and Further Transformations of the Resultant Dihydropyridines. Advanced Synthesis & Catalysis 2016, 358 (18), 2912-2922 DOI: 10.1002/adsc.201600412.
Kolská, K.; Ghavre, M.; Pour, M.; Hybelbauerová, S.; Kotora, M. Total Synthesis of Coibacin D by Using Enantioselective Allylation and Metathesis Reactions. Asian Journal of Organic Chemistry 2016, 5 (5), 646-651 DOI: 10.1002/ajoc.201600022.
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