Publications

Found 7 results
Author Title [ Type(Desc)] Year
Filters: Author is D. Phillip Cox  [Clear All Filters]
Journal Article
Machara, A.; D. Cox, P.; Hudlicky, T. ChemInform Abstract: Synthesis of Nalbuphine from Oripavine via N-Demethylation of N-Cyclobutylmethyl Oripavine. ChemInform 2012, 43 (19), no-no DOI: 10.1002/chin.201219209.
Murphy, B.; Šnajdr, I.; Machara, A.; Endoma-Arias, M. Ann A.; Stamatatos, T. C.; D. Cox, P.; Hudlicky, T. Conversion of Thebaine to Oripavine and Other Useful Intermediates for the Semisynthesis of Opiate-Derived Agents: Synthesis of Hydromorphone. Advanced Synthesis & Catalysis 2014, 356 (11-12), 2679-2687 DOI: 10.1002/adsc.201400445.
Machara, A.; D. Cox, P.; Hudlicky, T. Direct Synthesis of Naltrexone by Palladium-Catalyzed N -Demethylation/Acylation of Oxymorphone: The Benefit of CH Activation and the Intramolecular Acyl Transfer from C-14 Hydroxy. Advanced Synthesis & Catalysis 2012, 354 (14-15), 2713-2718 DOI: 10.1002/adsc.201200677.
Machara, A.; Endoma-Arias, M. Ann A.; Císařová, I.; D. Cox, P.; Hudlicky, T. Direct Synthesis of Noroxymorph­one from Thebaine: Unusual Ce IV Oxidation of a Methoxydiene-Iron Complex to an Enone-γ-Nitrate. European Journal of Organic Chemistry 2016, 2016 (8), 1500-1503 DOI: 10.1002/ejoc.201600153.
Machara, A.; Werner, L.; Endoma-Arias, M. Ann; D. Cox, P.; Hudlicky, T. Improved Synthesis of Buprenorphine from Thebaine and/or Oripavine via Palladium-Catalyzed N-Demethylation/Acylation and/or Concomitant O-Demethylation. Advanced Synthesis & Catalysis 2012, 354 (4), 613-626 DOI: 10.1002/adsc.201100807.
Werner, L.; Machara, A.; Adams, D. R.; D. Cox, P.; Hudlicky, T. Synthesis of Buprenorphine from Oripavine via N-Demethylation of Oripavine Quaternary Salts. The Journal of Organic Chemistry 2011, 76 (11), 4628-4634 DOI: 10.1021/jo200567n.
Werner, L.; Wernerova, M.; Machara, A.; Endoma-Arias, M. Ann; Duchek, J.; Adams, D. R.; D. Cox, P.; Hudlicky, T. Unexpected N -Demethylation of Oxymorphone and Oxycodone N -Oxides Mediated by the Burgess Reagent: Direct Synthesis of Naltrexone, Naloxone, and Other Antagonists from Oxymorphone. Advanced Synthesis & Catalysis 2012, 354 (14-15), 2706-2712 DOI: 10.1002/adsc.201200676.
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