| Title | Beta-cyclodextrin-modified monolithic stationary phases for capillary electrochromatography and NANO-HPLC chiral analysis of ephedrine and ibuprofen |
| Publication Type | Journal Article |
| Year of Publication | 2002 |
| Authors | Pumera M, Jelinek I, Jindrich J, Benada O |
| Journal | Journal of Liquid Chromatography & Related Technologies |
| Volume | 25 |
| Issue | 16 |
| Pagination | 2473 - 2484 |
| Date Published | 2002/// |
| ISBN Number | 1082-6076 |
| Keywords | duplicate |
| Abstract | Chiral monolithic capillary columns for reversed-phase capillary electrochromatography (CEC) and for nano-HPLC were prepared by linking beta-cyclodextrin modifier into the acrylic monolithic phase. Columns with the physically and chemically bonded beta-cyclodextrin derivatives were tested under CEC and nano-HPLC conditions; enatioselective separation of (-)-ephedrine/ (+)-pseudoephedrine and (+/-)-ibuprofen was successfully performed. The separation efficiency of CEC and HPLC was examined and compared; resolution of (+/-) ibuprophen was 2.45 and 2.97 for CEC and HPLC respectively, number theoretical plates of thiourea were 41,600N/m in CEC. |
| URL | http://apps.isiknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=2&SID=Q2aIOAe32iKPO787Bf4&page=1&doc=13&cacheurlFromRightClick=no |
| Short Title | J. Liq. Chromatogr. Relat. Technol. |
